Titlebook: Drug-Induced Lung Injury; Masayuki Hanaoka,Hiroyuki Nakamura,Kazutetsu Aoshi Book 2018 Springer Nature Singapore Pte Ltd. 2018 DLI.Periphe

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Clinical Characteristics of DLI: What Are the Clinical Features of DLI? elevated value was 138 cases. As treatment, the suspected drug was discontinued in 159 cases, and corticosteroids including pulse therapy were used in 132. The outcomes were relatively favorable, ranging from a complete cure to an improved condition in 142 cases, but there were 5 fatalities.

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Blood Tests for the Diagnosis and/or Management of DLI: What Are the Clinical Significances of KL-6,ct the efficacy of the treatment or the outcome in patients with DLI. Additionally, the drug-induced lymphocyte stimulation test can in part provide supportive information about the causative agents of DLI.

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Book 2018es, and for which the only treatment is to discontinue taking the drug. Very little clinical evidence regarding the disorder is available, since randomized trials cannot to be carried out, the onset of the disorder cannot be predicted, and the resulting pathological condition is life-threatening. Ho

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Diagnostic Approach for DLI: How is DLI Diagnosed?sidered, while also differentiating it from the worsening of a pulmonary/pleural lesion that a patient may have already had as an underlying disease and from the opportunistic infections—particularly when the patient has reduced immunity and defense against such infections.

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Imaging Features of Drug-Induced Interstitial Lung Disease: How HRCT of DLI Is Interpreteding chronic fibrosing interstitial pneumonia as risk of DLI, early detection of DLI, diagnosis of DAD-type DLI for the estimation of prognosis, aids to differential diagnosis, follow-up examination including evaluation of treatment effect, and so on.

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Differential Diagnoses of DLI: What Are the Differential Diagnoses of DLI?duced. Some considerations could be pneumonia caused by an opportunistic infection, exacerbation of underlying disease, or other unrelated diseases. The differential diagnoses of drug-induced lung injury are described in this chapter.

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erefore, clinical, radiological, and histopathological findings vary among patients. The management of DLI caused by DMARDs includes the tentative discontinuation of the DMARDs, considering a thorough differential diagnosis, and the initiation of antibiotics, such as trimethoprim/sulfamethoxazole, and moderate- to high-dose glucocorticoids.

从容

Perfect Intentions, Imperfect Peoples, interferon, herbal medicine, and molecularly targeted drugs frequently cause DILD. Checkpoint inhibitors can also cause severe interstitial lung disease (ILD) as one of a variety of side effects associated with their immunomodulatory function.

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bronchiolitis obliterans and pulmonary hypertension are being reported; further, these are drug-induced conditions. Clinicians should be more aware of DLI symptoms caused by herbal medication and interrogate patients regarding their use of herbal medication and supplements as well as prescription drugs.