| 书目名称 | Drug Toxicity in Embryonic Development I |
| 副标题 | Advances in Understa |
| 编辑 | Robert J. Kavlock (Director),George P. Daston |
| 视频video | http://file.papertrans.cn/284/283139/283139.mp4 |
| 丛书名称 | Handbook of Experimental Pharmacology |
| 图书封面 |  |
| 描述 | Having received the invitation from Springer-Verlag to produce a volume on drug-induced birth defects for the Handbook of Experimental Pharmacology, we asked ourselves what new approach could we offer that would capture the state of the science and bring a new synthesis of the information on this topic to the world‘s literature. We chose a three-pronged approach, centered around those particular drugs for which we have a relatively well established basis for understanding how they exert their unwanted effects on the human embryo. We then supplemented this information with a series of reviews of critical biological processes involved in the established normal developmental patterns, with emphasis on what happens to the embryo when the processes are perturbed by experimental means. Knowing that the search for mechanisms in teratology has often been inhibited by the lack of understanding of how normal development proceeds, we also included chapters describing the amazing new discoveries related to the molecular control of normal morphogenesis for several organ systems in the hope that the experimental toxicologists and molecular biologists will begin to better appreciate each others q |
| 出版日期 | Book 1997 |
| 关键词 | Geburtsschaden; Morphogenese; abnormal development; birth; birth defects; drug; drugs; embryo; morphogenesis |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-60445-4 |
| isbn_softcover | 978-3-642-64408-5 |
| isbn_ebook | 978-3-642-60445-4Series ISSN 0171-2004 Series E-ISSN 1865-0325 |
| issn_series | 0171-2004 |
| copyright | Springer-Verlag Berlin Heidelberg 1997 |
|Archiver|手机版|小黑屋|
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