Titlebook: Drug Targets in Cellular Processes of Cancer: From Nonclinical to Preclinical Models; Hardeep Singh Tuli Book 2020 The Editor(s) (if appli

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Theorie wirtschaftspolitischer Reformen have mostly designed in a way that they can revert apoptotic abnormalities or induce apoptosis. This book chapter discusses the apoptotic process and its abnormalities in cancer cells, and how chemotherapeutic drugs can induce apoptosis, with most advanced and updated findings on mechanisms of action.

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Pharmacologic Modulation of the Immune Response Against Tumours in the Elderly,the elderly, metformin and valproic acid, have been shown to have anti-neoplastic effects. These effects suggest that therapeutic approaches in the elderly should be carefully analysed. Clinical trials are required to assess the exact role of immune response and therapy in tumour incidence and survival in the elderly.

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Apoptotic Cell Death: Important Cellular Process as Chemotherapeutic Target, have mostly designed in a way that they can revert apoptotic abnormalities or induce apoptosis. This book chapter discusses the apoptotic process and its abnormalities in cancer cells, and how chemotherapeutic drugs can induce apoptosis, with most advanced and updated findings on mechanisms of action.

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Inflammatory Mediators: Potential Drug Targets in Cancer,ey are also found to induce inhibition of inflammation via p38/MAPK and PI3K/Akt and COX-2 activity. In the present chapter, the advancements in understanding the inflammation-mediated cancer progression and associated preclinical/clinical studies will be discussed.