书目名称 | Drug Safety Evaluation | 副标题 | Methods and Protocol | 编辑 | Jean-Charles Gautier | 视频video | | 概述 | Features a compendium of analytical technologies, including some review chapters, with a focus on clarity and applicability in real life laboratory practice.Contains methods and techiques easily trans | 丛书名称 | Methods in Molecular Biology | 图书封面 |  | 描述 | Non-clinical drug safety evaluation, the assessment of the safety profile of therapeutic agents through the conduct of laboratory studies in in vitro systems and in animals, is an essential step in the progress of new pharmaceuticals heading toward the ultimate goal of clinical trials and, eventually, approval.In Drug Safety Evaluation: Methods and Protocols, expert researchers detail a compendium of analytical technologies with a focus on clarity and applicability in real life laboratory practice.These meticulous contributions feature key topics such as acute to chronic general toxicity studies, histopathology studies, reproductive toxicity studies, genotoxicity studies, safety pharmacology studies, investigative toxicity studies, and safety biomarker studies.As a volume in the highly successful Methods in Molecular Biology™ series, chapters include brief introductions to their respective subjects, lists of the necessary materials, step-by-step, readily reproducible protocols, and tips on troubleshooting and avoiding known pitfalls.Comprehensive and authoritative, Drug Safety Evaluation: Methods and Protocols serves as an ideal guide to this field, helpful to pharmaceutical scient | 出版日期 | Book 2011 | 关键词 | Carcinogenicity; Chemical protein adducts; Developmental toxicity; Experimental design; General toxicity | 版次 | 1 | doi | https://doi.org/10.1007/978-1-60761-849-2 | isbn_softcover | 978-1-4939-5669-2 | isbn_ebook | 978-1-60761-849-2Series ISSN 1064-3745 Series E-ISSN 1940-6029 | issn_series | 1064-3745 | copyright | Springer Science+Business Media, LLC 2011 |
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