Titlebook: Drug Resistance in Cancer: Mechanisms and Strategies; Sameer Ullah Khan,Fayaz Malik Book 2024 The Editor(s) (if applicable) and The Author

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Drug Resistance in Cancer: Mechanisms and Strategies978-981-97-1666-1

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enge by employing combinatorial therapies that can prove to be useful and effective. Overall the book reflects on the current treatment challenges, futuristic strategies and new research initiatives that explore novel treatment options..978-981-97-1668-5978-981-97-1666-1

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Introduction to Drug Resistance in Cancer,g drugs, novel strategic options with better efficacy need to be explored that overcome resistance. Combination therapy is a widely used alternative with a better success rate though the risk of amplified side effects is commonplace. However, recent groundbreaking immune therapy combination with the

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Tumor Microenvironment: Multiway Role in Drug Resistance,ys, cellular cross talk, and microenvironmental factors, and the chapter highlights the contribution of TME-driven adaptive strategies such as immune evasion, epithelial-mesenchymal transition, and angiogenesis to therapeutic resistance. It also highlights specific facets including the role of cance

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Intracellular Compartments and Drug Resistance,apeutic agents. Likewise, mitochondria’s involvement in drug resistance is multifaceted, encompassing alterations in energy production, reactive oxygen species (ROS) generation, and apoptotic signaling. Mitochondrial dysfunction can confer resistance to apoptosis-inducing drugs, allowing cancer cell

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