Titlebook: Drug Resistance in Bacteria, Fungi, Malaria, and Cancer; Gunjan Arora,Andaleeb Sajid,Vipin Chandra Kalia Book 2017 Springer International

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Role of External and Environmental Factors in Drug Resistance Emergence: Gut Microbiota,ironment in a variety of ways, food being a significant point of entry. Consequently, all of the above factors contribute to an increasing number of drug-resistant genes in the gut microbiome. To add to this phenomenon, transmission of these genes through members of the microbiome may occur by horiz

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Efflux-Mediated Drug Resistance in ,,no single EPI has been approved for use in clinical settings because of uncertainty around their potency and their intolerable adverse effects, particularly inhibition of cytochrome P450. Currently, the use of test active EPIs is limited to epidemiological studies. However, the search for more speci

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Current Antifungal Therapy and Drug Resistance Mechanisms in Dermatophytes,ous side effects, drug resistance in dermatophytes is rare. However, several recent cases of drug resistance in dermatophytes are beginning to emerge. Here, we describe the available therapeutics against fungal infections and some of the resistance mechanisms in fungi and finally highlight the curre

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Functional Roles of Highly Conserved Amino Acid Sequence Motifs A and C in Solute Transporters of t This natural passage barrier is essentially overcome with the use of integral membrane proteins known as solute transporters. These transport systems translocate solutes across the membrane such as in the case of bacterial drug and multidrug resistance efflux pumps. One of the largest groups of tra

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How Pathogens Survive Drug Pressure?,y chromosomal replication. On the account of a few vital antibiotic agents, point mutation of chromosomally encoded proteins is the essential instrument for resistance. Another procedure that may add to the development of resistance in the course of treatment is adaptive or induced change. Notwithst