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Titlebook: Drug Repurposing for Emerging Infectious Diseases and Cancer; Ranbir Chander Sobti,Sunil K. Lal,Ramesh K. Goyal Book 2023 The Editor(s) (i

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发表于 2025-3-21 18:03:47 | 显示全部楼层 |阅读模式
书目名称Drug Repurposing for Emerging Infectious Diseases and Cancer
编辑Ranbir Chander Sobti,Sunil K. Lal,Ramesh K. Goyal
视频video
概述Highlight different drug repositioning strategies against infectious disease and cancer.Summarizes computational approaches that are used in drug repositioning studies.Presents experimental models to
图书封面Titlebook: Drug Repurposing for Emerging Infectious Diseases and Cancer;  Ranbir Chander Sobti,Sunil K. Lal,Ramesh K. Goyal Book 2023 The Editor(s) (i
描述.​This book presents drug repurposing strategies to combat infectious diseases and cancer. It discusses key experimental and .in silico. approaches for modern drug repositioning, including signature matching, molecular docking, genome-wide associated studies, and network-based approaches aided by artificial intelligence. Further, the book presents various computational and experimental strategies for better understanding disease mechanisms and identify repurposed drug candidates for personalized pharmacotherapy. It also explores the databases for drug repositioning, summarizes the approaches taken for drug repositioning, and highlights and compares their characteristics and challenges. Towards the end, the book discusses challenges and limitations encountered in computational drug repositioning..
出版日期Book 2023
关键词Drug repurposing; Approach technologies; Cancers; Infectious diseases; Polypharmacology
版次1
doihttps://doi.org/10.1007/978-981-19-5399-6
isbn_softcover978-981-19-5401-6
isbn_ebook978-981-19-5399-6
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor
The information of publication is updating

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发表于 2025-3-22 01:27:52 | 显示全部楼层
Ranbir Chander Sobti,Sunil K. Lal,Ramesh K. GoyalHighlight different drug repositioning strategies against infectious disease and cancer.Summarizes computational approaches that are used in drug repositioning studies.Presents experimental models to
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发表于 2025-3-22 11:49:59 | 显示全部楼层
Benedikt Korf,Timothy Raeymaekerss such as drug repurposing are required to develop therapeutics to treat both common and rare disorders. Drug repurposing is a potential approach in drug discovery for identifying new therapeutic applications for existing medications that are distinct from the original medical indication. Identifica
发表于 2025-3-22 16:16:15 | 显示全部楼层
Benedikt Korf,Timothy Raeymaekersby shifting the focus from one target-one drug model to a multi-target approach. Polypharmacology uses comprehensive detailed knowledge about the composition of the drug, pathogenesis course of its mode of action, drug toxicology, pharmacodynamics, pharmacokinetics, and their side effects. Drug phar
发表于 2025-3-22 18:41:24 | 显示全部楼层
Markus Virgil Hoehne,Dereje Feyissarates big datasets that are mined to identify previously unknown drug–event combinations, and, as an extension, may help in identifying new indications for old drugs. The therapeutic potential of a drug using pharmacovigilance-based drug repurposing can be assessed in one of the four ways—serendipit
发表于 2025-3-22 22:41:36 | 显示全部楼层
Jennifer Feather,Catherine E. Thomas level of expression in the cerebellar cortex and hippocampus. According to cellular protein–protein interactor analysis, it appears to play a role in transcription control. Protein–protein interactions play fundamental roles in physiological roles such as cell proliferation, gene regulation, cell s
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Jennifer Feather,Catherine E. Thomasecome important due to new findings about their diverse pharmacological actions. Here in this chapter, we described about the repurposed use of flavonoids to treat different types of lung cancers such as small-cell lung cancer and non–small-cell lung cancer. The flavonoids covered in this chapter ar
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