Titlebook: Drug Discovery from Mother Nature; Subash Chandra Gupta,Sahdeo Prasad,Bharat B. Aggar Book 2016 The Editor(s) (if applicable) and The Auth

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Capsaicin and Its Role in Chronic Diseases,ointestinal disorders or cancer, since evidence demonstrates that the oral or local application of capsaicin reduce inflammation and pain in rheumatoid arthritis, promotes gastric protection against ulcer and induces apoptosis of the tumour cells. Sadly, these results have been paralleled by conflic

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The Role of Indirubins in Inflammation and Associated Tumorigenesis,earing substituents mainly in the 5- and 3′-position suitable for improved solubility and inhibition against CDKs and GSK3ß, referred to as canonical indirubins. Interestingly, several noncanonical 7- and 7′-indirubin derivatives have been reported, showing a distinct binding model in the ATP-bindin

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Eucalyptol and Its Role in Chronic Diseases,ignaling pathways and radical scavenging. The effects of eucalyptol have been studied in several cell and animal models as well as in patients with chronic diseases. Furthermore, eucalyptol can pass the blood–brain barrier and hence can be used as a carrier to deliver drugs to the brain via a microe

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Koos van Nugteren,Patty Joldersmaalculated using a density functional theory method. Dimers of eugenol and its related compounds showed large antioxidant activities and high ω values and also exerted efficient anti-inflammatory activities. Eugenol appears to possess multiple antioxidant activities (dimerization, recycling, and chel