Titlebook: Drug Discovery and Evaluation: Methods in Clinical Pharmacology; Franz J. Hock,Michael R. Gralinski Reference work 2020Latest edition Spri

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https://doi.org/10.1007/978-3-8350-9323-2ucosal, and local. Furthermore, a targeted and individualized approach for drug monitoring was developed that takes into account individual patient variability through careful gathering of pharmacokinetic and pharmacodynamic data: therapeutic drug monitoring, allowing to really individualize patient

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https://doi.org/10.1007/978-3-8351-9065-8 citing their advantages and limitations, along with simulations for optimizing treatment regimens. Furthermore, it describes the applications of pharmacodynamic models for treatment of bacterial infections and, finally, the pathophysiological conditions leading to treatment failures and strategies

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Das kapitalistische Patriarchatmay provide accurate predictions of the dose-effect relationships by advancing the understanding of target engagement as well as exposure response and therefore has the potential to improve the decision making regarding the optimal dose and schedules as well as risk-benefit assessments for later sta

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Reference work 2020Latest editionlects the current state of the art in Clinical Pharmacology...Drug Discovery and Evaluation has become a more and more difficult, expensive and time-consuming process. The effect of a new compound has to be detected by in vitro and in vivo methods of pharmacology. The activity spectrum and the poten

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h institutes and in industry.Helps establish official guidel.This is the second edition of a well-received book in the series “Drug Discovery and Evaluation” The completely revised new edition of the volume reflects the current state of the art in Clinical Pharmacology...Drug Discovery and Evaluatio

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Dietmar Wellisch,Maik Näth,Kerstin Thielemus-pituitary-adrenal-gonadal axis, while thyroid disorders are viewed separately..There is a focus on the hormone receptor interaction similarities and the drug-ligand-receptor binding..The concept of hormone agonists and antagonists has a prominent place..Neuroendocrinology pharmacodynamic evaluation is not included in this chapter.

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Methodologies of Safety Assessment in Clinical Pharmacology for what duration and whether these side effects can be monitored and whether they are reversible. The terminology for the safety assessment of drugs has some specifics that need to be explained right at the beginning of this chapter.

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