Titlebook: Drug Discovery and Development; Michael Williams,Jeffrey B. Malick Book 1987 The Humana Press Inc. 1987 autoimmune disease.cannabinoid.dev

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Cimetidine and Other Histamine H2-Receptor AntagonistsThe treatment of peptic ulcer disease (both duodenal and gastric ulcers) and other acid-related diseases has been revolutionized by the discovery of the antagonist drugs that act at the histamine H.-receptor.

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https://doi.org/10.1007/978-1-4612-4828-6autoimmune disease; cannabinoid; development; drug; drug discovery; drugs; dynamics; ethanol; methodology; ne

解脱

978-1-4612-9180-0The Humana Press Inc. 1987

尖

https://doi.org/10.1007/978-3-7091-1654-8e compound in the test tube. The discovery of a novel chemical entity that modulates some aspect of cell or tissue function is but the first step in the drug development process. Once shown to be selective and efficacious, a compound must also be relatively free of toxicity, bioavailable, and market

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Leif Erik Walther Prof. Dr. med. habil.successful program is a clearly delineated strategy based on quantitative pharmacological assays. The particular problem chosen often will influence this strategy and dictate the type of approach; that is, either a rational or an empirical one. Depending on this selection, the synthetic targets then

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https://doi.org/10.1007/978-3-7091-3097-1The first of these has been the increased availability of powerful, but relatively inexpensive, computer systems in both academic and industrial research laboratories. This provided researchers with direct access to a level of computational capacity that had previously been available only on large a

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Wie einheitlich ist „ein Instinkt“?drug, the question of relevance must be ascertained. The biologist usually interprets the effects of a drug on isolated tissues or organs as an action at the receptor level. However, the question does not have to be targeted toward a particular cellular or mechanistic parameter; it can also be more

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