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Titlebook: Drug Delivery and Targeting; Monika Schäfer-Korting,Ulrich S. Schubert Book 2024 The Editor(s) (if applicable) and The Author(s), under ex

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发表于 2025-3-21 18:15:24 | 显示全部楼层 |阅读模式
书目名称Drug Delivery and Targeting
编辑Monika Schäfer-Korting,Ulrich S. Schubert
视频video
概述Integrates drug delivery, pharmacology and therapy.Bridges chemistry, physics of the vehicle and innovative drugs.Maximizes reader insights into cutting-edge therapies
丛书名称Handbook of Experimental Pharmacology
图书封面Titlebook: Drug Delivery and Targeting;  Monika Schäfer-Korting,Ulrich S. Schubert Book 2024 The Editor(s) (if applicable) and The Author(s), under ex
描述Since the publication of the Handbook of Experimental Pharmacology Vol. 197 in 2010 there have been important advances in drug development, drug delivery and – more recently – drug targeting. This is in particular relevant with the new generation of drugs acting on the immune system and tumors. These are quite often accompanied by major adverse reactions. Safe therapy is, therefore, an important area of research, in particular in chronic diseases and in persons of old age. In addition, the Covid-19 pandemic has brought renewed attention to vaccinations against viral infections, and mRNA vaccines have been tested for vaccination in tumor therapy, too. Vaccine delivery has stimulated important research on carriers which may pave the way for other applications and enhance a path to e.g. CRISPR-cas therapy..
出版日期Book 2024
关键词Drug carrier interactions; drug targeting; anticancer drugs; vaccines; small molecules; proteins; nucleic
版次1
doihttps://doi.org/10.1007/978-3-031-52864-4
isbn_softcover978-3-031-52866-8
isbn_ebook978-3-031-52864-4Series ISSN 0171-2004 Series E-ISSN 1865-0325
issn_series 0171-2004
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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发表于 2025-3-21 20:34:14 | 显示全部楼层
Anwendung der Verhaltensmedizinities in treating and healing diseases. In addition to viral gene transfer, the overwhelming power of non-viral mRNA-based vaccines is driving the development of novel gene transporters. Thereby, various nucleic acids such as DNA (pDNA) or RNA (mRNA, siRNA, miRNA, gRNA, or ASOs) need to be delivered
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https://doi.org/10.1007/978-3-662-48124-0ng them into patient-friendly formulations: they are often unstable and have a tendency to aggregate or degrade upon storage. As a result, the vast majority of protein actives are delivered parenterally as solutions, which has a number of disadvantages in terms of cost, accessibility, and patient ex
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Verfahren der Fertigungssteuerungty against infections and diseases. According to the types of infectious diseases and the required immunity, adjuvants with various acting mechanisms have been designed and applied in human vaccines. In this chapter, we introduce the advances in vaccine adjuvants based on nanomaterials and small mol
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Verfahren der Fertigungssteuerunguding drug-loaded polymeric microparticles, implants (preformed and in situ forming), oil-based solutions, and aqueous suspension have been established. In this chapter, we summarize all the marketed technology platforms and discuss their challenges regarding development including but not limited to
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Steuerungsrelevante Fertigungsmerkmaleiological action of drug delivery systems has led to a better insight into the design principles of drug delivery systems. TEM can be applied for particle characterization, for the visualization of the uptake and intracellular pathways of drug vehicles in cells and tissues and more recently can be a
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Peter Eberl,Malte Frederik Mölleritates the transport of nutrients into the central nervous system (CNS) and exchanges metabolites but restricts passage of blood-borne neurotoxic substances and drugs/xenobiotics into CNS. BBB plays a crucial role in maintaining the homeostasis and normal physiological functions of CNS but severely
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