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Titlebook: Drug Delivery System; Kewal K. Jain Book 2014Latest edition Springer Science+Business Media, New York 2014 chemical engineering.drug deliv

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EDV / Ultraschall / Chordozenteseenhancing drug delivery to the brain is of great importance in diagnostics and therapeutics of central nervous system (CNS) diseases. In this context, nanoparticles are an emerging class of drug delivery systems that can be easily tailored to deliver drugs to various compartments of the body, includ
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Vorposten der Gesundheitspflegeme. There is currently no cure available for any neurodegenerative disease, and the existing therapeutic interventions only alleviate the symptoms of the disease. The advances in the drug discovery research have come to a halt with a lack of effective means to deliver drugs at the targeted site. In
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Microfluidic-Based Manufacture of siRNA-Lipid Nanoparticles for Therapeutic Applications,s. In this chapter we describe a novel microfluidic-based manufacturing process for the rapid manufacture of siRNA-LNP, together with protocols for characterizing the size, polydispersity, RNA encapsulation efficiency, RNA concentration, and total lipid concentration of the resultant nanoparticles.
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https://doi.org/10.1007/978-3-662-37803-8Recent studies have shown the ability of mesenchymal stem cells (MSCs) to migrate toward and engraft into the tumor sites, which provides a potential for their use as carriers for cancer gene therapy. Here, we describe the strategies of using MSCs as carriers for cancer gene therapy using a nonviral transfection method.
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