Titlebook: Drug Delivery; Materials Design and Eric P. Holowka,Sujata K. Bhatia Textbook 2014 Springer Science+Business Media New York 2014 Controlled

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https://doi.org/10.1007/978-3-662-29503-8 applications in delivery of drug dosage forms. These approaches largely focus on the viewpoint that the drug is housed in a system that is steadily or immediately affected by its external environment.

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Thin-Film Materials,ur discussion in Chap. . to ., traditionally entering the bloodstream through hydrolysis in the stomach, or ., done at the site of treatment. Since drug delivery encompasses a broad spectrum of treatment methodologies, we can ask two basic questions:

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Controlled-Release Systems,proximately $150 million is invested over a 10-year period in the design and implementation of new drug offerings [1]. These drug offerings typically have a narrow therapeutic index (i.e., the difference between toxic and therapeutic levels). Additionally, there is patient-related physiological fati

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Self-Microemulsifying Materials,the advantages of bulk and surface erosion. In Chap. ., we addressed the control over fabricated shape in the form of a thin film with the effects and applications in delivery of drug dosage forms. These approaches largely focus on the viewpoint that the drug is housed in a system that is steadily o

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Targeted Materials,e drug dosage form. This can be approached from the perspective of engineering the material to be responsive to the environment either . or . the tissue. We discuss the first approach in this chapter and the second approach later in Chap. ..

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Hydrogel Materials,or enzymatic), erosion (i.e., surface or bulk), and swelling (i.e., crosslinks). In the case of swellable systems, we limited our focus only to the adjustment of swelling characteristics based on changing the crosslink density, polymer molecular weight between crosslinks, and hydrophilicity. These u