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Titlebook: Drebrin; From Structure and F Tomoaki Shirao,Yuko Sekino Book 2017 The Editor(s) (if applicable) and The Author(s), under exclusive license

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发表于 2025-3-21 18:15:39 | 显示全部楼层 |阅读模式
书目名称Drebrin
副标题From Structure and F
编辑Tomoaki Shirao,Yuko Sekino
视频video
概述Offers the first comprehensive review of drebrin from its molecular structure and function to the physiological and pathological roles edited by the discoverer of drebrin.Presents a multidisciplinary
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Drebrin; From Structure and F Tomoaki Shirao,Yuko Sekino Book 2017 The Editor(s) (if applicable) and The Author(s), under exclusive license
描述This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as a marker of dementia in neurological disorders such as Alzheimer’s disease. Since drebrin was first identified by our group in 1985, many studies of drebrin have been done in various fields, including not only molecular biology, biophysics, cell biology, neuroscience, clinical studies, spermatogenesis, immunology, and cancer metastasis, but others as well. The structure of this book facilitates the understanding of the whole picture of studies on drebrin. The volume begins with a general introduction to drebrin, and then the chapters in the second part provide the basic knowledge for further understanding. The third part examines its function in the nervous system, and the fourth part discusses its function in the non-nervous system. This work will appeal to researchers who are interested in cytoskeletal dynamics at membrane-cytoskeletal interface as well as the number of them who use drebrin as a tool, such as a mar
出版日期Book 2017
关键词Actin filament; Cell migration; Process formation; Synapse formation; Synaptic plasticity; Adherens junct
版次1
doihttps://doi.org/10.1007/978-4-431-56550-5
isbn_softcover978-4-431-56817-9
isbn_ebook978-4-431-56550-5Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Japan KK
The information of publication is updating

书目名称Drebrin影响因子(影响力)




书目名称Drebrin影响因子(影响力)学科排名




书目名称Drebrin网络公开度




书目名称Drebrin网络公开度学科排名




书目名称Drebrin被引频次




书目名称Drebrin被引频次学科排名




书目名称Drebrin年度引用




书目名称Drebrin年度引用学科排名




书目名称Drebrin读者反馈




书目名称Drebrin读者反馈学科排名




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Advances in Experimental Medicine and Biologyhttp://image.papertrans.cn/e/image/282822.jpg
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Multi-sense Attention for Autonomous Agentsein, which is classified into two major isoforms produced by alternative splicing from a single . gene. The isoform predominantly expressed in the adult brain (drebrin A) is neuron specific, containing a neuron-specific sequence (Ins2) in the middle of the molecule. Drebrin A is highly concentrated
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https://doi.org/10.1007/978-3-031-04386-4in in vivo, we must understand its molecular properties. In this chapter, I will focus on the purification and characterization of drebrin in vitro. Drebrin binds to F-actin with a stoichiometry of 1:5~6 with a .. of 1~3 × 10. M and strongly inhibits the binding of other actin-binding proteins such
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Nikolaos Karagiannis,Debbie A. Mohammedyclonal and monoclonal antibodies. Immunoblot analysis demonstrated that the adult drebrin isoform (drebrin A) is restricted to neural tissues, while the embryonic drebrin isoforms (drebrin E1 and E2 in chicken and drebrin E in mammals) are found in a wide variety of tissues. In the developing brain
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Nikolaos Karagiannis,Debbie A. Mohammedn is an F-actin-binding protein that increases noticeably during juvenile synaptogenesis. Electron microscopic analysis reveals that drebrin is highly enriched specifically on the postsynaptic side of excitatory synapses. Since dendritic spines are structures specialized for excitatory synaptic tran
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