书目名称 | Diverse Effects of Hypoxia on Tumor Progression |
编辑 | M. Celeste Simon |
视频video | |
概述 | Hypoxia, defined as reduced oxygen tension, is a common physiological phenomenon in both normal embryonic development and malignancy progression Hypoxia promotes cancer progression by regulating vario |
丛书名称 | Current Topics in Microbiology and Immunology |
图书封面 |  |
描述 | Hypoxia, defined as reduced oxygen tension, is a common physiological phenomenon in both normal embryonic development and malignancy progression.Although severe hypoxia is generally toxic for both normal tissue and tumors, neoplastic cells gradually adapt to prolonged hypoxia though additional genetic and genomic changes with a net result that hypoxia promotes tumor progression and therapeutic resistance. Hypoxia promotes cancer progression by regulating various aspects of cancer biology, including radiotherapy resistance, metabolism, angiogenesis and invasion/migration |
出版日期 | Book 2010 |
关键词 | angiogenesis; biology; cancer stem cell maintenance; cancer-associated fibroblasts; carcinoma; cells; glio |
版次 | 1 |
doi | https://doi.org/10.1007/978-3-642-13329-9 |
isbn_softcover | 978-3-642-26484-9 |
isbn_ebook | 978-3-642-13329-9Series ISSN 0070-217X Series E-ISSN 2196-9965 |
issn_series | 0070-217X |
copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |