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Titlebook: Diseases of the Pituitary; Diagnosis and Treatm Margaret E. Wierman Book 1997 Humana Press Inc. 1997 Gonadotropin.growth.growth hormone.hor

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Growth Hormone,land. In addition to GH, some somatotrophs also produce prolactin and the glycoprotein alpha-subunit. Somatotrophs comprise approximately 35–50% of human anterior pituitary cells and are distributed throughout the gland, with a possible preponderance in the lateral portions. The human anterior pitui
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Growth Hormone Deficiency,is an essential component in monitoring childhood health and development. During the first few years of life, a child’s height can cross percentile lines on a growth chart, reflecting, at least in part, his or her genetic makeup. After this time, children grow in a relatively predictable manner and
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Acromegaly,by a monoclonal pituitary adenoma. Elevated GH and insulin-like growth factor-I (IGF-I) levels, if left untreated, lead to disfigurement, severe morbidity, and increased mortality. Early diagnosis and aggressive treatment will ameliorate or reverse symptoms and improve patient outcome.
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ACTH,s preserve the body’s homeostatic integrity under basal and stress conditions. It is striking that the structural and functional determinants regulating the HPA axis are strongly conserved across mammalian species. Thus, this unique system has served the adaptation to physiologic and psychologic str
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