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Titlebook: Disease Gene Identification; Methods and Protocol Johanna K.‘DiStefano Book 2018Latest edition Springer Science+Business Media, LLC 2018 bi

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发表于 2025-3-21 17:56:40 | 显示全部楼层 |阅读模式
书目名称Disease Gene Identification
副标题Methods and Protocol
编辑Johanna K.‘DiStefano
视频video
概述Includes cutting-edge methods and protocols.Provides step-by-step detail essential for reproducible results.Contains key notes and implementation advice from the experts
丛书名称Methods in Molecular Biology
图书封面Titlebook: Disease Gene Identification; Methods and Protocol Johanna K.‘DiStefano Book 2018Latest edition Springer Science+Business Media, LLC 2018 bi
描述.This volume presents detailed laboratory procedures in an easy to follow format that can be carried out with success by investigators lacking previous exposure to a specific research method. Chapter guide readers through the application of molecular approaches to disease gene identification and overviews,  and case studies are also presented. Written in the highly successful .Methods in Molecular Biology .series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls..Authoritative and practical, .Disease Gene Identification: Methods and Protocols, Second Edition .aims to help with. .the identification and characterization of many more disease-related genes and provide novel, and effective strategies for disease treatment and prevention..
出版日期Book 2018Latest edition
关键词biomarker discovery; exome sequencing; ChIP assay; CRISPR; Parkinson’s
版次2
doihttps://doi.org/10.1007/978-1-4939-7471-9
isbn_softcover978-1-4939-8496-1
isbn_ebook978-1-4939-7471-9Series ISSN 1064-3745 Series E-ISSN 1940-6029
issn_series 1064-3745
copyrightSpringer Science+Business Media, LLC 2018
The information of publication is updating

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Microbiome Sequencing Methods for Studying Human Diseaseste high-throughput sequencing platform. We conclude with a review of the fundamental concepts of data analysis and interpretation for these kinds of experiments. Our goal is to provide the reader with the essential knowledge needed to undertake microbiome experiments for application to human disease
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The Emerging Role of Long Noncoding RNAs in Human Diseasegenesis, thereby challenging the concept that protein-coding genes are the sole contributors to the development of human disease. This chapter highlights recent findings linking lncRNAs with human diseases of complex etiology, including hepatocellular carcinoma, Alzheimer’s disease, and diabetes.
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Primary Airway Epithelial Cell Gene Editing Using CRISPR-Cas9culture, expansion, selection, and differentiation of AECs, which allow the robust generation of a bulk edited AEC population from transduced cells. Applying these methods, we detail here our latest protocol to generate mucociliary epithelial cultures knocked out for a specific gene from donor-isola
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Kristian Dahl Hertz,Philip Haldingduction to precision medicine, discuss the importance of identifying genes and genetic variants that contribute to disease development and progression, offer examples of approaches that can be applied to treat specific diseases, and present some of the current challenges and limitations of precision
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