| 书目名称 | Discrimination of Mobile Supramolecular Chirality |
| 副标题 | Acylative Molecular |
| 编辑 | Ayumi Imayoshi |
| 视频video | |
| 概述 | Nominated by Kyoto University as an outstanding Ph.D. thesis.Presents a detailed description and a variety of examples of molecular transformations.Enables understanding of qualitatively novel asymmet |
| 丛书名称 | Springer Theses |
| 图书封面 |  |
| 描述 | This book proposes a novel concept for molecular recognition. In the field of asymmetric synthesis approaching the mature science, asymmetric discrimination and catalytic synthesis of chiral supramolecules still stand as unsolved problems. The extreme difficulty in asymmetric synthesis of such supramolecules may result from the mobile nature of supramolecular chirality. Here the author shows the first highly enantioselective synthesis of mechanically chiral supramolecules. In the presence of a chiral organocatalyst, a mechanically planar chiral rotaxane was obtained with p erfect enantiopurity (>99% ee) with an excellent selectivity. The dynamic and flexible recognition mode enabled asymmetric synthesis of supramolecules with conformational flexibility and mobility. The recognition mode of the catalyst is a contrast to the traditional static and rigid recognition mode of the typical conventional catalysts. The concept of dynamic molecular recognition will be adopted as a novelconcept in a wide range of fields beyond the field of organic chemistry, including material chemistry, biochemistry, and medicinal chemistry.. |
| 出版日期 | Book 2022 |
| 关键词 | Asymmetric synthesis; Synthesis of chiral supramolecules; Rotaxane; Molecular transformations; Molecular |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-981-16-7431-0 |
| isbn_softcover | 978-981-16-7433-4 |
| isbn_ebook | 978-981-16-7431-0Series ISSN 2190-5053 Series E-ISSN 2190-5061 |
| issn_series | 2190-5053 |
| copyright | Springer Nature Singapore Pte Ltd. 2022 |
发表于 2025-3-21 17:13:40
