书目名称 | Discovery DMPK Quick Guide | 副标题 | Guide to Data Interp | 编辑 | S. Cyrus Khojasteh,Harvey Wong,Cornelis E.C.A. Hop | 视频video | | 概述 | Highlights assays, parameters to be optimized, candidate properties, and assessment.Contains a large amount of reference data that are useful for day-to-day interpretation of ADME studies.Multi discip | 图书封面 |  | 描述 | .This book is intended for a broad readership, in particular, those working or interested in drug discovery coming from various disciplines such as medicinal chemistry, pharmacology, drug metabolism and pharmacokinetics, bioanalysis, clinical sciences, biochemistry, pharmaceutics, and toxicology. It provides, for the first time, a completely integrated look at multiple aspects of ADME sciences (absorption, distribution, metabolism, and excretion) in a summary format that is clear, concise, and self-explanatory. DMPK in Drug Discovery - Guide to Data Interpretation and integration leverages the prior knowledge from the first book that covers the basics of each concept (Drug Metabolism and Pharmacokinetics Quick Guide). This reference book is meant to be used day to day and provides many useful tables (used for data interpretation), figures, and case studies that can facilitate drug discovery. The case studies are intended to be short and relevant to the topic discussed and present another dimension to the discussions.. | 出版日期 | Book 2022 | 关键词 | Drug discovery; Drug optimization; ADME; Drug candidate selection; Metabolic CL; Prodrug; PKPD Modeling; PB | 版次 | 1 | doi | https://doi.org/10.1007/978-3-031-10691-0 | isbn_softcover | 978-3-031-10693-4 | isbn_ebook | 978-3-031-10691-0 | copyright | Springer Nature Switzerland AG 2022 |
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