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Titlebook: Directed Drug Delivery; A Multidisciplinary Ronald T. Borchardt,Arnold J. Repta,Valentino J. S Book 1985 The Humana Press Inc. 1985 bioche

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Müfit Bahadir,Harun Parlar,Michael Spitellercollaboration that continued for over 4 years between 1969 and 1972. Higuchi’s laboratory played a major role in developing the first two therapeutic system products, which have embodied a number of pharmaceutical “firsts”. These are the pilocarpine ocular therapeutic system and the progesterone ute
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Müfit Bahadir,Harun Parlar,Michael Spitellergy and biochemical defects responsible for disease processes the drug industry has moved from large scale screening operations to much more rational approaches to drug design in which active molecules are synthesized and tested on the basis of .. measurements of interactions with specific receptors
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Müfit Bahadir,Harun Parlar,Michael Spitellers in drug distribution only to the surface of the brain. Another approach to circumventing the BBB involves drug latentiation or the conversion of water soluble substances to lipid soluble compounds. This approach portends a vast promise for the neuropharmaceutical industry, which has yet to be real
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Müfit Bahadir,Harun Parlar,Michael Spitelleruse my assignment is to talk about drug transport in skin and my first job after receiving my Ph.D. in 1956 was to study factors influencing drug transport across skin at the University of Wisconsin under a Defense Department contract directed by Tak and Dale Wurster.
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Müfit Bahadir,Harun Parlar,Michael Spitelleression is the basis for many systems that are even claimed to be new today. This development was a milestone in area of physical pharmacy and dosage form development. Tak has been a driving force in the field of pharmacy: he gave people a mission and has been a source of inspiration. I was a low tem
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Müfit Bahadir,Harun Parlar,Michael Spiteller7.4, and become progressively more labile as the pH is lowered. A major rationale for developing this system was a need for a polymer capable of a wide variety of erosion rates and where erosion could be confined to the surface of a solid device. Then, any selected, constant release rate can be achi
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Müfit Bahadir,Harun Parlar,Michael Spiteller agents. Since active targeting such as antibody or receptor-mediated delivery will be mentioned in other chapters, discussions will be limited to the use of conjugates in which a drug is associated or covalently bound to a non-specific macro-molecular carrier. Emphasis will be placed on the results
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