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Titlebook: Dipeptidyl Aminopeptidases in Health and Disease; Nathan Back,Irun R. Cohen,Rodolfo Paoletti Book 2003 The Editor(s) (if applicable) and T

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书目名称Dipeptidyl Aminopeptidases in Health and Disease
编辑Nathan Back,Irun R. Cohen,Rodolfo Paoletti
视频video
丛书名称Advances in Experimental Medicine and Biology
图书封面Titlebook: Dipeptidyl Aminopeptidases in Health and Disease;  Nathan Back,Irun R. Cohen,Rodolfo Paoletti Book 2003 The Editor(s) (if applicable) and T
描述.Proceedings of the International Conference on Dipeptidyl Aminopeptidases, held September 26-28, 2002, in Berlin, Germany. ..Dipeptidyl Aminopeptidases exert a potent modulatory role at an interface between immune mechanisms, metabolic responses and neuroendocrine pathways. Experimental models and clinical studies addressing the role of these enzymes and the effect of specific inhibitors pave the way to novel therapeutic concepts in immunology, rheumatology, oncology, reproductive medicine and diabetes. ..Leading experts in this field have contributed to this book which presents a state-of-the-art view on these enzymes, at a time when our understanding of their function is growing ever more rapidly and therapeutic options become imminent. The sections of the book focus on various topics: ..- Structure and function of dipeptidyl aminopeptidases, .- DPP IV-like proteins, .- Immune mechanisms and immune disorders, .- Cancer and angiogenesis, .- Diabetes and metabolism, .- Therapeutic implications. .
出版日期Book 2003
关键词Alanin; Antigen; Chemokine; Glutamat; Transplantation; enzymes; metabolism; proteins
版次1
doihttps://doi.org/10.1007/b105297
isbn_softcover978-1-4757-8730-6
isbn_ebook978-0-306-47920-5Series ISSN 0065-2598 Series E-ISSN 2214-8019
issn_series 0065-2598
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Science+Busines
The information of publication is updating

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Re-Uptake Mechanisms of Peptide Fragments after DPP IV-Mediated Proteolysis in the Peripheral Nervouot ganglia of the species guinea pig by employing immunohistochemistry. This finding provides new insights into the fate of peptide fragments, following DPP IV-mediated proteolysis. The results indicate, that the fragments may be re-utilized via uptake mechanisms in the peripheral nervous system of
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Dipeptidyl Peptidase IV Gene Familyopeptidase activity with the closely related enzymes DPIV and FAP. The similarities between DP8, DP9 and DPIV in tissue expression pattern suggest a potential role for DP8 and DP9 in liver disease, T cell activation and immune function. The role of the two novel enzymes DP8 and DP9 and the other non
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Investigation of DP IV-dependent Protein-Protein Interactions using Surface Plasmon Resonancesubstances which can interfere with such interactions with extracellular matrix proteins..Our data suggest the hypothesis that one ore more components localised at the membrane fraction are involved in DP IV mediated binding of cells on extracellular matrix.
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