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Titlebook: Dilemmas in Diabetes; Stewart Wolf,Beatrice Bishop Berle Book 1975 The Editor(s) (if applicable) and The Author(s), under exclusive licens

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,Glucagon and Other Hormones — A New Perspective, in the sense that some of the cells of the hypophysis function, but rather as a single, coordinated if not coupled functional unit designed to control the flux of key nutrients into and out of cells in accordance with supply and demand. This view was based on the remarkable qualitative relationship
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Structural Aspects of Islet Cell Membranes,asic lesion(s) responsible for endocrine pancreatic dysfunction in this disease remain(s) to be unraveled. Although membrane systems are known to be of major importance in the control of cellular activities, no information is so far available concerning the possible role of the membranes as a crucia
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Microvascular Lesions,herosclerosis. The former accounts for most of the deaths in juvenile-onset diabetics, and the latter for most of those in adult-onset diabetics. Microangiopathy is present in the majority of diabetics previous to the development of demonstrable glucose intolerance ( 126), and progresses in spite of
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Markus Ottersbach,Andrea Platte,Lisa Rosenracturing techniques) and reveals individual components of these membranes down to a macromolecular size, namely 20 to 30 angstroms. With this technique, the interior of the membranes (middle of the bilayer) is exposed (13, 109), and appears structurally differentiated into smooth areas interrupted
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