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Titlebook: Digital Twins; Tools and Concepts f Christoph Herwig,Ralf Pörtner,Johannes Möller Book 2021 The Editor(s) (if applicable) and The Author(s)

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发表于 2025-3-21 20:06:52 | 显示全部楼层 |阅读模式
书目名称Digital Twins
副标题Tools and Concepts f
编辑Christoph Herwig,Ralf Pörtner,Johannes Möller
视频video
概述First book to provide an overview of the role of digital twins in bioprocessing.Describes fundamental concepts and tools.Explores new and efficient methods for research and development, and smart manu
丛书名称Advances in Biochemical Engineering/Biotechnology
图书封面Titlebook: Digital Twins; Tools and Concepts f Christoph Herwig,Ralf Pörtner,Johannes Möller Book 2021 The Editor(s) (if applicable) and The Author(s)
描述This is the first of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization..Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during research and development, as well as during tech transfer and routine manufacturing. ..In this regard, one promising tool is the use of digital twins, which offer a virtual representation of the bioprocess. They reflect the mechanistics of the biological system and the interactions between process parameters, key performance indicators and product quality attributes in the form of a mathematical process model. Furthermore, digital twins allow us to use computer-aided methods to gain an improved process understanding, to test and plan novel bioprocesses, and to efficiently monitor them. ..This book explains the mathematical structure of digital twins, their development and the model’s respective parts, as well as concepts for the knowledge-dri
出版日期Book 2021
关键词Process modeling; Digitalization; Biopharmaceutical production; Virtual instrumentation; Industry 4; 0
版次1
doihttps://doi.org/10.1007/978-3-030-71660-8
isbn_softcover978-3-030-71662-2
isbn_ebook978-3-030-71660-8Series ISSN 0724-6145 Series E-ISSN 1616-8542
issn_series 0724-6145
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl
The information of publication is updating

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发表于 2025-3-21 23:29:08 | 显示全部楼层
When Is an In Silico Representation a Digital Twin? A Biopharmaceutical Industry Approach to the Di a brief retrospect on their history and expectations for their deployment in today’s business environment, and a detailed financial assessment of their attractive economic benefits are provided in this chapter. The argument that restrictive guidelines set forth by regulatory agencies would hinder t
发表于 2025-3-22 01:10:22 | 显示全部楼层
Digitalization and Bioprocessing: Promises and Challenges,While advances in synthetic biology and metabolic engineering have made it possible to produce thousands of new molecules from cells, few of these molecules have reached the market. The traditional methods of strain and bioprocess development that transform laboratory results to industrial processes
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发表于 2025-3-22 09:19:10 | 显示全部楼层
Digital Seed Train Twins and Statistical Methods,oduction processes, which contain several challenging development and process steps. One of these steps is the time- and cost-intensive cell proliferation process (also called seed train) to increase cell number from cell thawing up to production scale. Challenges like complex cell metabolism, batch
发表于 2025-3-22 13:45:32 | 显示全部楼层
Mechanistic Mathematical Models as a Basis for Digital Twins,re detailed virtual representations of bioprocesses with predictive capabilities. In biotechnology, Digital Twins can be used to monitor processes and to provide data for process control and optimization. Central and crucial components of Digital Twins are mathematical process models, which are capa
发表于 2025-3-22 19:26:59 | 显示全部楼层
发表于 2025-3-23 00:09:26 | 显示全部楼层
0724-6145 ficient methods for research and development, and smart manuThis is the first of two volumes that together provide an overview of the latest advances in the generation and application of digital twins in bioprocess design and optimization..Both processes have undergone significant changes over the p
发表于 2025-3-23 03:45:25 | 显示全部楼层
Book 2021cess design and optimization..Both processes have undergone significant changes over the past few decades, moving from data-driven approaches into the 21st-century digitalization of the bioprocess industry. Moreover, the high demand for biotechnological products calls for efficient methods during re
发表于 2025-3-23 08:48:21 | 显示全部楼层
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