Titlebook: Diagnostic Pathology of Hematopoietic Disorders of Spleen and Liver; Ling Zhang,Haipeng Shao,Serhan Alkan Book 2020 Springer Nature Switze

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Hairy Cell Leukemia, Hairy Cell Leukemia Variant, and Splenic Diffuse Red Pulp Small B-Cell Lymphomlymphoma/leukemia, unclassifiable as provisional entities according to the 2016 World Health Organization (WHO) classification. The clinicopathologic features of all rare lymphomas involving the spleen will be discussed in this chapter.

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Histiocytic and Dendritic Cell Disorders in the Liver and Spleen,c findings to make a unifying diagnosis. Recently, strong emphasis on the molecular signature of these disorders gives an opportunity to better describe, subclassify, and ultimately treat these rare disorders/neoplasms.

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Anatomy and Histology of Normal Liver and Spleen,adjacent to the left lower ribs, stomach, left kidney, tail of the pancreas, and colon. It is usually not palpable on physical examination, but may be felt in children, adolescents, and thin adults. The organ is extremely vulnerable to injury especially when the body experiences external trauma. Acc

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Diagnostic Approaches to Hematopoietic Disorders of the Spleen and Liver, organ for filtration, immune regulation, and hematopoiesis during fetal development. Although the intact immune modulation from the spleen would protect human beings from diseases, there are a number of primary and secondary hematologic malignancies that may occur when immunity of the spleen is com

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Molecular and Genetic Diagnostic Approaches of Hematopoietic Disorders of the Spleen and Liver,ts. It is widely accepted that these hematopoietic diseases are mostly driven by genetic alterations including gene deletion, amplification, translocation, karyotypic rearrangements, mutations, or epigenetic changes. Understanding the gene profiles of a hematopoietic disorder helps us to have better

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Hairy Cell Leukemia, Hairy Cell Leukemia Variant, and Splenic Diffuse Red Pulp Small B-Cell LymphomPL) are a group of small mature B-cell lymphomas that often involved the spleen, blood, and bone marrow. HCL accounts for only 2% of lymphoid leukemias and HCL-V and SDRPL are even rare. HCL shows characteristic morphology of kidney-bean-shaped nuclei and abundant clear cytoplasm with cytoplasmic ha

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Plasma Cell Neoplasms and Amyloidosis in the Liver and Spleen,ized primary plasmacytoma or extramedullary dissemination of plasma cell myeloma (PCM)/plasma cell leukemia (PCL). The latter is far more common and biologically distinct from primary plasmacytoma. Extramedullary myeloma is an aggressive disease associated with high risk cytogenetic/molecular featur