用户名  找回密码
 To register

QQ登录

只需一步,快速开始

扫一扫,访问微社区

Titlebook: Diagnosis and Treatment of Parkinson’s Disease — State of the Art; H. Przuntek,T. Müller Conference proceedings 1999 Springer-Verlag Wien

[复制链接]
查看: 31722|回复: 50
发表于 2025-3-21 16:22:46 | 显示全部楼层 |阅读模式
书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art
编辑H. Przuntek,T. Müller
视频video
丛书名称Journal of Neural Transmission. Supplementa
图书封面Titlebook: Diagnosis and Treatment of Parkinson’s Disease — State of the Art;  H. Przuntek,T. Müller Conference proceedings 1999 Springer-Verlag Wien
描述Expert clinicians and basic scientists with a special interest in Parkinson’s disease review the current state of science and clinical therapeutics of the disease. Therefore these articles represent an authorative review of the current state of knowledge regarding preclinical course and symptomatology, subtypes with their impact on the pathology, genetic alterations, novel mechanisms of neuronal cell death, diagnostic tools and old and novel therapeutic approaches with respect to neuroprotection and neuroregeneration in Parkinson’s disease. Particular emphasis has been placed on a novel antiparkinsonian drug called budipine with various modes of action also influencing altered non dopaminergic systems in Parkinson’s disease. It is evident, that many questions on the cause, course and treatment of Parkinson’s disease are still unanswered and therefore the ideal way to treat a parkinsonian patient remains to be defined.
出版日期Conference proceedings 1999
关键词Budipin; Budipine; Neurogeneration; Neuronaler Zelltod; Neuroprotektion; neuronal cell death; neuroprotect
版次1
doihttps://doi.org/10.1007/978-3-7091-6360-3
isbn_softcover978-3-211-83275-2
isbn_ebook978-3-7091-6360-3Series ISSN 0303-6995
issn_series 0303-6995
copyrightSpringer-Verlag Wien 1999
The information of publication is updating

书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art影响因子(影响力)




书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art影响因子(影响力)学科排名




书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art网络公开度




书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art网络公开度学科排名




书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art被引频次




书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art被引频次学科排名




书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art年度引用




书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art年度引用学科排名




书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art读者反馈




书目名称Diagnosis and Treatment of Parkinson’s Disease — State of the Art读者反馈学科排名




单选投票, 共有 1 人参与投票
 

0票 0.00%

Perfect with Aesthetics

 

1票 100.00%

Better Implies Difficulty

 

0票 0.00%

Good and Satisfactory

 

0票 0.00%

Adverse Performance

 

0票 0.00%

Disdainful Garbage

您所在的用户组没有投票权限
发表于 2025-3-21 23:09:33 | 显示全部楼层
发表于 2025-3-22 02:00:41 | 显示全部楼层
Multiple mechanisms of action: the pharmacological profile of budipine,nding studies at native muscarinic M.-M. and human recombinant ml-m5 receptor subtypes in vitro, is up to 125-fold weaker than that of biperiden and corresponds to its approximately 100-fold lower potency to cause experimentally-induced peripheral antimuscarinic effects and explains only part of its
发表于 2025-3-22 04:54:47 | 显示全部楼层
,Mechanism and consequences of nerve cell death in Parkinson’s disease,echanism of nerve cell death. Furthermore, oxygen free radicals are also involved in an oxygen-dependent pro-apoptotic pathway stimulated by the inflammatory reaction observed in Parkinson’s disease. These data suggest that anti-oxidant or anti-inflammatory treatments may slow down the progression o
发表于 2025-3-22 08:43:48 | 显示全部楼层
,Functional imaging of Parkinson’s disease: is it possible to detect brain areas for specific sympto pallidotomy or high frequency electrical subthalamic stimulation..Activation studies suggest that Parkinsonian rest tremor arises from a combination of inappropriate overactivity of cerebellar connections and loss of dopaminergic function. When tremor is relieved by ventral thalamotomy or thalamic
发表于 2025-3-22 12:53:27 | 显示全部楼层
,Tremorlytic activity of budipine in Parkinson’s disease, (SNR) to 7.2 ± 1.6. However, the latter result was statistically not significant, probably due to the small patient number. In the placebo-group (n = 7) there was no reduction of tremor occurrence or of tremor intensity. The CURS sum score was improved from 5.7 to 3.0 in the budipine group, whereas
发表于 2025-3-22 18:32:29 | 显示全部楼层
发表于 2025-3-22 23:37:27 | 显示全部楼层
发表于 2025-3-23 04:10:46 | 显示全部楼层
0303-6995 evident, that many questions on the cause, course and treatment of Parkinson’s disease are still unanswered and therefore the ideal way to treat a parkinsonian patient remains to be defined.978-3-211-83275-2978-3-7091-6360-3Series ISSN 0303-6995
发表于 2025-3-23 08:42:44 | 显示全部楼层
Planning a Study at the Cluster Levelrect loop” to SN zona reticulata (SNZR) and medial pallidum (GPI) leading to inhibition of the glutamatergic thalamo-cortical motor loop and reduced cortical activation. b) The tremor-dominant type shows more severe neuron loss in medial than in lateral SNZC and damage to the retrorubral field A8 co
 关于派博传思  派博传思旗下网站  友情链接
派博传思介绍 公司地理位置 论文服务流程 影响因子官网 SITEMAP 大讲堂 北京大学 Oxford Uni. Harvard Uni.
发展历史沿革 期刊点评 投稿经验总结 SCIENCEGARD IMPACTFACTOR 派博系数 清华大学 Yale Uni. Stanford Uni.
|Archiver|手机版|小黑屋| 派博传思国际 ( 京公网安备110108008328) GMT+8, 2025-5-21 15:53
Copyright © 2001-2015 派博传思   京公网安备110108008328 版权所有 All rights reserved
快速回复 返回顶部 返回列表