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Titlebook: Diabetic Retinopathy; Current Pharmacologi Michael W. Stewart Book 2017 Mayo Foundation for Medical Education and Research 2017 Alpha agoni

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Treatment of Diabetic Retinopathy: A Historical Perspective,m type 1 diabetes and the total number of patients affected with type 2 diabetes was much lower than it is today. The introduction of insulin in 1922 extended survival for patients with type 1 diabetes mellitus (DM), but life expectancy remained poor because many died of disease-related complication
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Targeting Vascular Endothelial Growth Factor,etic retinopathy (PDR) – for several decades with level I evidence emerging from the Early Treatment of Diabetic Retinopathy Study [45] and the Diabetic Retinopathy Study (DRS) [166–168]. Laser reduced the risk of severe vision loss (<5/200) in eyes with PDR and moderate vision loss (>15 letters) in
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Corticosteroids: Targeting Multiple Cytokines and Chemokines,ell to regimens that include repeated intravitreal injections. A significant minority of patients (approximately 40%), however, exhibit an inadequate response and require additional or alternate therapy. In the phase III anti-VEGF registration trials, laser photocoagulation served as secondary thera
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Current Treatment Recommendations,ore the introduction of potent pharmacotherapy for DR, early diagnosis of DR followed by prompt laser photocoagulation to eyes at risk of vision loss was the most effective way to stabilize vision [23]. Significant improvements in visual acuity (VA) were rarely achieved in patients with established
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