Titlebook: Diabetic Neuropathy; Advances in Pathophy Solomon Tesfaye,Christopher H. Gibbons,Aristidis V Book 2023Latest edition The Editor(s) (if appl

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https://doi.org/10.1007/978-3-476-05421-0 the nervous system and that deficient neurotrophic support contributes to diabetic neuropathy. It also considers the opportunity emerging from these observations—that delivery of exogenous neurotrophic factors or other means of manipulating neurotrophic support may be viable approaches to preventin

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https://doi.org/10.1007/978-3-476-05421-0agnose as they have different underlying pathophysiology, may be misdiagnosed as the other forms of neuropathies with similar clinical manifestations and perhaps most importantly may respond to immunotherapy or other therapeutic interventions. This chapter describes the asymmetric diabetic neuropath

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https://doi.org/10.1007/978-3-476-05421-0y, including imaging techniques and muscle biopsies; however, these methods are mainly used for research purposes. Currently, there are no specific treatments for motor neuropathy, but recent evidence indicates strength benefits from physical training of motor dysfunction in individuals with DSPN. I

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https://doi.org/10.1007/978-3-476-05421-0define several possible psychosocial routes linking DPN to depression/anxiety and impaired QoL, thereby providing clinicians with the specific points for interventions to alleviate emotional distress and improve QoL. While most of the existing treatments to-date are focused on pharmacological manage

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https://doi.org/10.1007/978-3-476-05421-0phenotyping of neuropathy and neuropathic pain have not yet been fully developed. As will be apparent from other chapters in this book, the phenotype of neuropathy is ideally captured by a combination of relevant patient reported outcomes, examination findings and investigations such as nerve conduc