Titlebook: Diabetic Cardiomyopathy; Biochemical and Mole Belma Turan,Naranjan S. Dhalla Book 2014 Springer Science+Business Media New York 2014 Cardio

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Cellular Mechanism Underlying the Misfunction of Cardiac Ionic Channels in Diabetestes affects the amplitude and kinetics of most of the potassium currents by modifying the biophysical behavior and even the expression levels of the potassium channel-forming proteins. We review here the effects of diabetes mellitus on individual currents, as well as the intracellular mechanisms tha

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Role of PPAR-δ in Diabetic Cardiomyopathyrect cellular insult to the myocardium. Several investigations, mainly echocardiographic population-based studies, documented a uniform association between diabetic cardiomyopathy and the presence of cardiac hypertrophy and myocardial stiffness. In the following review, we attempt to provide a compr

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Liver and Fat in Type 2 Diabetes: New Insights and Clinical Relevanceer is emerging as one of the principal organs involved in insulin resistance associated with type 2 diabetes mellitus. The liver is involved both short- as well as long-term maintenance of glucose concentrations in the blood. In type 2 diabetes, impaired insulin-mediated suppression of glucose produ

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Metabolic Alterations in Diabetic Cardiomyopathyserved in this diabetic population. These mechanisms are likely to act synergistically and are believed to potentiate one another. Hyperglycemia is an essential factor in the development of cardiomyopathy and exerts its effects by altering protein kinase C, increasing oxidative stress and causing ab

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