| 书目名称 | Diabetes, Insulin and Alzheimer‘s Disease | | 编辑 | Suzanne Craft,Yves Christen | | 视频video | | | 概述 | Includes supplementary material: | | 丛书名称 | Research and Perspectives in Alzheimer‘s Disease | | 图书封面 |  | | 描述 | .Neurons share more similarities with insulin-producing pancreatic islet cells than with any other cell type. The root of this similarity may lie in the islet’s evolution from an ancestral insulin-producing neuron. The islet-neuron connection becomes less surprising as we learn more about insulin’s involvement in functions far from its traditional role in mediating glucose uptake in muscle. The importance of insulin in the regulation of corporal aging has been established by the dramatic increases in longevity experienced by animals in which the adipose insulin receptor has been genetically eliminated, or in which the insulin-related daf genes have been mutated. New research suggests that, analogous to its influence on corporal aging, insulin also makes important contributions to brain aging and the expression of late-life neurodegenerative disease. Insulin plays a key role in cognition and other aspects of normal brain function. Insulin resistance induces chronic peripheral insulin elevations and is associated with reduced insulin activity both in periphery and brain. The insulin resistance syndrome underlies conditions such as Type 2 diabetes mellitus and hypertension, which are | | 出版日期 | Book 2010 | | 关键词 | Alzheimer; Alzheimer´s disease; Diabetes; Insulin; aging; brain-insulin connection; growth factor; insulin | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-642-04300-0 | | isbn_softcover | 978-3-642-26281-4 | | isbn_ebook | 978-3-642-04300-0Series ISSN 0945-6066 Series E-ISSN 2196-310X | | issn_series | 0945-6066 | | copyright | Springer-Verlag Berlin Heidelberg 2010 |
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书目名称Diabetes, Insulin and Alzheimer‘s Disease影响因子(影响力)学科排名
书目名称Diabetes, Insulin and Alzheimer‘s Disease网络公开度
书目名称Diabetes, Insulin and Alzheimer‘s Disease网络公开度学科排名
书目名称Diabetes, Insulin and Alzheimer‘s Disease被引频次
书目名称Diabetes, Insulin and Alzheimer‘s Disease被引频次学科排名
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发表于 2025-3-21 16:54:02
