Titlebook: Diabetes Epidemiology, Genetics, Pathogenesis, Diagnosis, Prevention, and Treatment; Enzo Bonora,Ralph A. DeFronzo Reference work 2018 Spr

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Management of Process Excellencetic architecture ranges from highly penetrant monogenetic diseases, such as MODY and neonatal diabetes, to polygenic diseases, such as type 1 and type 2 diabetes that are caused by numerous genetic variants adding up to the individual risk. While both diabetes and diabetic complications have been kn

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Stefan Novotny,Nicholas Rohmannitially noninsulin requiring but with immune markers of type 1 diabetes (T1DM)..The prevalence of LADA has been estimated in a number of multicenter studies of both European and non-European populations. Around 4–14% of patients classified with T2DM have diabetes associated autoantibodies. Among the

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https://doi.org/10.1007/978-3-030-35020-8 Prediabetes are increasing and by 2040 it is estimated that there will be 642 million cases of diabetes alone worldwide, with many more people having Prediabetes. Type 2 diabetes can remain undiagnosed for many years and therefore screening can bring forward diagnosis, allowing treatment to be star

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Dioxins and Dioxin-like Compounds,ted to affect 592 million by 2035. Monitoring of glucose levels is an essential component of treatment - providing feedback to clinician and patient on management through lifestyle and pharmacotherapy. This chapter provides an overview of the evidence that monitoring levels of glycaemia leads to imp

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https://doi.org/10.1007/978-3-030-35020-8macrovascular complications. In diabetes care it is therefore essential to set appropriate glycemic targets (or target ranges) that guide the management of the disease in order to reduce the risk of long-term complications, while avoiding unnecessary burden or adverse events. In this chapter we disc

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Joyce A. Arditti,Casey M. McGregorsusceptible individuals, an environmental trigger initiates an immune response. The immune infiltration into pancreatic islets results in beta cell damage, impairment of beta cell function, and potential destruction of beta cells. Consequently, there have been a number of studies using immune interv

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