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Titlebook: Diabetes - Perspectives in Drug Therapy; Mathias Schwanstecher Book 2011 Springer-Verlag Berlin Heidelberg 2011 antidiabetic therapy.diabe

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Takehiko Kariya,James E. Rosenbaumrgy homeostasis that coordinates metabolic pathways in order to balance nutrient supply with energy demand. It is now recognized that pharmacological activation of AMPK improves blood glucose homeostasis, lipid profile, and blood pressure in insulin-resistant rodents. Indeed, AMPK activation mimics
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Historiography of Biogeography in Mexicocoid activity may play a role in the etiology of the metabolic syndrome. Consistent with this notion, elevated adipose expression of 11β-HSD1 induced metabolic syndrome-like phenotypes in mice. Thus, 11β-HSD1 is a proposed therapeutic target to normalize glucocorticoid excess in a tissue-specific ma
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,Al-Ghazali (Abū Ḥāmid al-Ghazālī),n insulin-sensitive organs leads to the progression of inflammation and induction of insulin resistance in obesity. This chapter explains the mechanisms involved in the inflammatory response during diabetes progression with specific attention to the IL-1β signal effects influencing insulin action an
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