书目名称 | Developmental Origins of Health and Disease (DOHaD) |
副标题 | From Biological Basi |
编辑 | Takeo Kubota,Hideoki Fukuoka |
视频video | |
概述 | Covers numerous diseases associated with DOHaD.Presents an update of our understanding of molecular mechanisms for DOHaD.Based on the latest biological data.Suggests importance of early interventions |
丛书名称 | Advances in Experimental Medicine and Biology |
图书封面 |  |
描述 | This book addresses the developmental origins of health and disease (DOHaD), a new medical concept that demonstrates that various adult diseases start in the fetal period. It discusses our current understanding of the molecular mechanisms of DOHaD, including gene body epigenetics and non-coding RNA, and comprehensively examines diseases such type 2 diabetes, a well known as standard DOHaD-associated disease, as well as non-alcoholic fatty liver disease, hypertension and neurodevelopmental disorders. It argues that most adult diseases start at a very early stage, such as in the fetal and neonatal periods, and that earlier prevention and intervention would result in better outcomes for adult diseases such as type 2 diabetes and cardiac disorders, which are increasing in both developed and developing countries. The book appeals to obstetricians and pediatricians, as well as physicians who treat adult patients, wanting to understand the origins of diseases.. |
出版日期 | Book 2018 |
关键词 | Epigenome; Pre-emptive medicine; Metabolic disease; Maternal under-nutrition; Nutritional environment |
版次 | 1 |
doi | https://doi.org/10.1007/978-981-10-5526-3 |
isbn_softcover | 978-981-13-3856-4 |
isbn_ebook | 978-981-10-5526-3Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
issn_series | 0065-2598 |
copyright | Springer Nature Singapore Pte Ltd. 2018 |