Titlebook: Development of the Cerebellum from Molecular Aspects to Diseases; Hassan Marzban Book 2023Latest edition The Editor(s) (if applicable) and

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Apoptosis, Autophagy, and Unfolded Protein Response and Cerebellar Development,velopment. Among these mechanisms, apoptosis, autophagy, and unfolded protein response play critical roles in regulating development by affecting cell fate. All of these pathways are involved in the regulation of cell numbers via determining the life and death cycles of the cells. In this chapter, w

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Schlemms-Canal

Epigenetic Control and Cerebellar Neurodevelopmental Disorders,s are not directly controlled by genomic DNA sequences and can be largely influenced by environmental factors. Epigenetic mechanisms include modification of DNA and DNA-bound proteins (histones), action of large and short regulatory RNA molecules, crosstalk between DNA and histone marks, nucleosome

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Hormonal Regulation of Cerebellar Development and Its Disorders,ic influences include hormonal signals from endocrine cells. Various hormone receptors are expressed in the cerebellum, and cerebellar function is greatly influenced by hormonal status. The aim of this chapter is to introduce several key features of hormones and their receptors involved in the regul

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胆小鬼

Primary Pediatric Brain Tumors of the Posterior Fossa: Part I,l diagnosis is provided in Table 1); this anatomic region also contains the pons and medulla, which along with the midbrain comprise the brainstem. In Part I of this comprehensive review, three important pediatric brain tumors usually localized to the cerebellum are discussed (and summarized in Tabl

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Primary Pediatric Brain Tumors of the Posterior Fossa: Part II A Comprehensive Overview of Medulloblar classification of these highly aggressive tumors. MB is divided into 4 molecular subgroups that exhibit different genomic alterations, gene expression profiles, response to treatment, and developmental cell of origin: WNT, Sonic Hedgehog (SHH), Group 3, and Group 4. Additional stratification int

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Cerebellar Developmental Disorders and Cerebellar Nuclei,outstanding developmental questions. We then describe recent progress in dissecting the lineages of cerebellar neurons that may point to new understanding of their involvement in congenital clinical disorders.