Titlebook: Development of Selective DNA-Interacting Ligands; Understanding the Fu Sefan Asamitsu Book 2020 The Editor(s) (if applicable) and The Autho

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https://doi.org/10.1007/978-3-8274-2724-3says. These results suggest that long-chain PI polyamide-Chl conjugates targeted to CAG/CTG repeats might be further developed toward potential chemical tools or drugs for trinucleotide repeat disorders.

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,Sequence-Specific DNA Alkylation and Transcriptional Inhibition by Long-Chain Hairpin Pyrrole–Imidasays. These results suggest that long-chain PI polyamide-Chl conjugates targeted to CAG/CTG repeats might be further developed toward potential chemical tools or drugs for trinucleotide repeat disorders.

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https://doi.org/10.1007/978-3-8274-2724-3iptional process have been performed with the aim of developing potential molecular probes and therapeutic agents for human diseases. This chapter summarizes the biological significance of DNA structures beyond the Watson–Crick structure and their interacting ligands.

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Grundlagen der Tektonik und Strukturgeologiepromoter of G4-containing DNA in the context of stable double-stranded DNA (dsDNA) under molecular crowding conditions. This cIKP might be applicable as a molecular probe for the detection of potential G4-forming sequences in dsDNA.

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Ligand-Mediated G-Quadruplex Induction in a Double-Stranded DNA Context by Cyclic Imidazole/Lysine promoter of G4-containing DNA in the context of stable double-stranded DNA (dsDNA) under molecular crowding conditions. This cIKP might be applicable as a molecular probe for the detection of potential G4-forming sequences in dsDNA.

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978-981-15-7718-5The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Singapor

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https://doi.org/10.1007/978-3-8274-2724-3bucil (Chl) conjugates targeted to CAG/CTG repeat sequences that are associated with trinucleotide repeat disorders. A high-resolution denaturing polyacrylamide sequencing gel analysis revealed sequence-specific alkylations by PI polyamide-Chl conjugates at the N3 of adenines or guanines in CAG/CTG