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Titlebook: Development of Chemistry-Based Screening Platform for Access to Mirror-Image Library of Natural Prod; Taro Noguchi Book 2018 Springer Natu

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Synthesis of Grb2 SH2 Domain Proteins for Mirror-Image Screening Systems, for easier preparation. Labeling at the N-terminus or the Ala. residue of the Grb2 SH2 domain provided functional probes to detect binding to a phosphotyrosine-containing peptide. The resulting synthetic-protein-based probes were applied to bioassays including chemical array analysis and enzyme-linked immunosorbent assays (ELISAs).
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https://doi.org/10.1007/978-3-663-10208-3products using a native protein (l-protein) in a mirror. In an effort to identify anticancer agents from the mirror-image natural products, chemical protein syntheses of some target oncoproteins, MDM2, MDMX and Grb2, and their applications to the chemical array screening process were achieved.
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Book 2018ing mirror-image proteins for the screening of available natural products, unavailable mirror-image isomers of natural products can be screened in a mirror process. Moreover, as mirror-image isomers including target proteins and natural products are mainly prepared by means of chemical synthesis, th
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Tools to Trace Truffles in Soiltates, on which state-based assertions can be conveniently formulated. As a result, we get the best of both worlds: on the one hand invariant-style representation of proof knowledge; on the other hand the bisimulation-based formal connection to the code.
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An International Analysis of Project Delivery Systems for Public Works Projectscontracting as the allocation of obligations, rights and risks among all parties) have been analysed. Then, the equivalence between these PDS and those defined by the Spanish Public Contracts Law has been established and an analysis of PDS used in Spain has been conducted.
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