Titlebook: Development and Engineering of Dopamine Neurons; R. Jeroen Pasterkamp,Marten P. Smidt,J. Peter H. B Book 2009 The Editor(s) (if applicable

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https://doi.org/10.1057/9780230801431esodiencephalic dopaminergic (mdDA) neurons..,. These factors have their own expression profile in the brain: Nurr1 is expressed in many forebrain regions, whereas Pitx3 is exclusively expressed in mdDA neurons. Functional analysis of the respective mouse mutants have emphasized the importance of bo

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https://doi.org/10.1057/9780230801431) subgroups, are generated from floor plate progenitors, rostral to the isthmic boundary. Floor plate progenitors are specified to become mDA progenitors between embryonic days 8.0 and 10.5. Subsequently these progenitors undergo neuronal differentiation in two phases, termed early and late differen

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Optik in bewegten Koordinatensystemen,d fibroblast growth factors. We summarize data obtained from animal models of Parkinson’s disease, review analyses of neurotrophin, neurotrophin receptor and FGF-2 knockout mice and put these into context with data obtained from patients with Parkinson’s disease and from postmortem studies. We provi

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