Titlebook: Dermal Drug Selection and Development; An Industrial Perspe Lionel Trottet,Howard Maibach, MD Book 2017 Springer International Publishing A

硬化

Introduction,y aspects of drug candidate selection in general to place into context the challenges that a drug discovery team would face for the selection of a dermal drug candidate. Finally, specific risks and opportunities for selecting such a dermal drug candidate are presented.

我要威胁

Assessing Drug Concentration in Skin: Direct and Indirect Methods,teristics: very specific for a drug or disease, possibly impractical, possibly not quantitative, possibly lacking sensitivity or possibly at a too early stage of development. They cannot, therefore, be applicable as versatile techniques for studying topical pharmacokinetics.

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细丝

FANG

https://doi.org/10.1007/978-3-319-59504-7drug development; dermal pharmacokinetics; dermal drugs; dermal drug candidate selection; dermatology

indignant

esculent

Lionel Trottet,Howard Maibach, MDThe only book of its kind that describes how the industry develops and selects dermal drugs, complete with its challenges and opportunities.Discusses how the science can be used for increased success

共同生活

揭穿真相

Confucianism and SustainabilityHistorically most topical drug classes seem to have been originally developed following the pragmatic principle that, “if an existing drug with an interesting pharmacology is effective orally/systemically, and the target is in the skin, it could well work topically without giving side effects and, therefore, would deserve to be tried topically”.

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