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Titlebook: Dermal Absorption and Decontamination; A Comprehensive Guid Aileen M. Feschuk,Rebecca M. Law,Howard I. Maibach Book 2022 The Editor(s) (if

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https://doi.org/10.1007/978-3-031-09349-4on, skin surface topography, etc. It may impact clinical use of topical drugs or percutaneous research including bioequivalence studies. Consequences may include less drug absorbed systemically or reduced rate of absorption. For quantitation studies and risk assessment, lateral spread may need to be incorporated as a “correction factor.”
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Mai Chi Vu,Nadia Singh,Irene Chu human), volatility, metabolic biotransformation/cutaneous metabolism, photochemical transformation and photosensitivity, excretion kinetics, lateral spread, and chemical method of determining percutaneous absorption.
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Twenty Clinically Pertinent Factors/Observations for Percutaneous Absorption in Humans, human), volatility, metabolic biotransformation/cutaneous metabolism, photochemical transformation and photosensitivity, excretion kinetics, lateral spread, and chemical method of determining percutaneous absorption.
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Experimental Variability in TEWL Data,onclusion regarding its effect, if such an effect exists, on TEWL metrics. Therefore, these variables require further research to determine their potential impact on TEWL. .: Matching for as many experimental variables as possible may reduce the disparity in TEWL data/conclusions.
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