Titlebook: Deep Brain Stimulation; A New Frontier in Ps Damiaan Denys,Matthijs Feenstra,Rick Schuurman Book 2012 Springer-Verlag Berlin Heidelberg 201

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,Neuropsychiatric Side Effects of Deep Brain Stimulation in Parkinson’s Disease,onmotor symptoms, including olfactory loss, autonomic failure, and psychiatric symptoms. Deep brain stimulation (DBS) of the subthalamic nucleus has been established as a highly effective treatment option for motor fluctuations and dyskinesia in advanced PD. However, psychiatric side effects after a

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,Psychiatric Aspects of Parkinson’s Disease in Animal Models of Deep Brain Stimulation of the Subthaase (PD). Unfortunately, these can be overshadowed by psychiatric side effects, including depression and suicide. The underlying mechanism is unknown, but it is generally believed that low mood is related to a dysfunction of the serotonin (5-hydroxytryptamine; 5-HT) system. Recent animal experiments

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Neurotransmitter Release During Deep Brain Stimulation,order, treatment-resistant depression, and Tourette’s syndrome. Despite its clinical efficacy, the mechanism of action of DBS is incompletely understood. Contrary to the previously proposed mechanism of local inhibition of neural elements at the stimulation site, recent studies have argued that DBS

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Book 2012tion for patients with therapy-refractory psychiatric disorders. The side-by-side presentation of clinical applications and animal research provides a truly translational approach. Also included is a special chapter on the ethical issues involved in deep brain stimulation in psychiatry..Deep brain s

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https://doi.org/10.1007/978-3-662-00963-5le. This chapter reviews the connectivities likely to be involved at different DBS sites on the basis of non-human-primate circuitry studies of the ventral anterior cingulate gyrus and orbital cortex.

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Physikalisch-chemisch bedingte Dermatosen,l trajectories surrounding DBS electrodes implanted in the SCC and VC/VS. Finally, we attempt to reconcile various data sets by presenting generalized hypotheses on potential therapeutic mechanisms of DBS for the treatment of psychiatric disorders.

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Genetik und Embryonalentwicklung der Hautand improved quality of life in patients with TRD and bipolar depression. To optimize patient outcomes, future challenges include understanding the neurophysiological and psychological adaptations that occur with continuous chronic stimulation of the SCC and the development of preoperative predictors of antidepressant response to SCC DBS.