Titlebook: Decoding Neural Circuit Structure and Function; Cellular Dissection Arzu Çelik,Mathias F. Wernet Book 2017 Springer International Publishi

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Recent Progress in the 3D Reconstruction of , Neural Circuitscanning microscopy (CLSM) or electron microscopy (EM) to analyze neuronal circuits found in the central nervous system (CNS) of the fruit fly. Comparisons of different algorithms and strategies for reconstructing neuronal circuits, using actual studies as references, will be discussed within this chapter.

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Targeted Manipulation of Neuronal Activity in Behaving Adult Flies together form a neural circuit controlling a specific behavior. This chapter provides a resource for researchers interested in examining how neurons and neural circuits contribute to the rich repertoire of behaviors performed by flies.

LIKEN

Paradigms for the Quantification of Behavioral Responses in Zebrafishs includes efficient transposon-mediated transgenesis and CRISPR/Cas9-mediated genome editing. These recent genetic advances in combination with the optical properties of the larva enable sophisticated neural circuit analyses, unsurpassed in any other vertebrate organisms.

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Visualization of Synapses and Synaptic Plasticity in the , Brainalso on the physiological properties of synaptic transmission and their plasticity. Techniques to detect many synapses at high resolution across many neurons in vivo and to access their physiology and plasticity are required. Here, we summarize recent genetic approaches to visualize synapses and to analyze synaptic plasticity in the . brain.

Engulf

The Current State of the Neuroanatomy Toolkit in the Fruit Fly ,model organisms, largely due to its sophisticated and expanding in vivo targeted neurogenetic manipulations. Here, we summarize the current status of techniques for precisely targeted spatiotemporal manipulation of the fly’s nervous system, focused on the most recent developments within the field.

optic-nerve

Retinal Connectomicsd degree of wiring specificity in retinal circuitry. This is only the beginning of what can be learned from the comprehensive mapping of retinal circuits. The field of retinal connectomics is rapidly contributing to the functional understanding of retinal computation and enabling wiring comparisons both within and across species.

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