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Titlebook: Deciphering Growth; Jean-Claude Carel,Paul A. Kelly,Yves Christen Conference proceedings 2005 Springer-Verlag Berlin Heidelberg 2005 IGF r

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State-of-the-Art DCN Topologiesnt animal groups — from microfauna (single-celled Foraminifera) to megafauna (dinosaurs) - and we discuss the possibility that natural selection and clade selection may pull body size in opposite directions. Despite size’s central importance, there is little evidence that body size differences among
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https://doi.org/10.1007/978-981-16-9368-7lood pressure indicate that other maternal genes could influence size at birth in first pregnancies, where risk of pre-eclampsia is greatest. In subsequent pregnancies, gestational diabetes is linked to increased risk of macrosomia, and the impact of higher maternal glucose levels on larger offsprin
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Johannes Hoogeveen,Andre-Marie Taptuéf the IGF-1R gene. In our mutant mice, the postnatal growth of males relied more strongly on IGF-1R levels than the growth of females. Experiments using tissue-specific IGF-1R inactivation in the central nervous system provided evidence that IGF signaling in the brain may play a key role during the
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https://doi.org/10.1007/978-0-387-34942-8ozygote for missense mutations in the ligand binding domain. These mutations lowered the affinity of the IGF receptor for IGF-I and attenuated receptor signaling. The other child had a stop codon in exon 2 and showed a reduction in cell surface IGF receptor abundance. Though specific mutations withi
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Putting IGF-I Biology into a Clinical Perspective,
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The Importance of the National Cooperative Growth Study (NCGS),
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