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Titlebook: Data Mining in Bioinformatics; Xindong Wu,Lakhmi Jain,Dennis Shasha Book 2005 Springer-Verlag London 2005 Alignment.Markov chain.XML.bioin

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书目名称Data Mining in Bioinformatics
编辑Xindong Wu,Lakhmi Jain,Dennis Shasha
视频video
概述No known book on this area.First book containing the work of key researchers in biological data mining.Presents new techniques on (a) gene expression data mining, (b) gene mapping for disease detectio
丛书名称Advanced Information and Knowledge Processing
图书封面Titlebook: Data Mining in Bioinformatics;  Xindong Wu,Lakhmi Jain,Dennis Shasha Book 2005 Springer-Verlag London 2005 Alignment.Markov chain.XML.bioin
描述8. 1. 1 Protein Subcellular Location The life sciences have entered the post-genome era where the focus of biologicalresearchhasshiftedfromgenomesequencestoproteinfunctionality. Withwhole-genomedraftsofmouseandhumaninhand,scientistsareputting more and more e?ort into obtaining information about the entire proteome in a given cell type. The properties of a protein include its amino acid sequences, its expression levels under various developmental stages and in di?erenttissues,its3Dstructureandactivesites,itsfunctionalandstructural binding partners, and its subcellular location. Protein subcellular location is important for understanding protein function inside the cell. For example, the observation that the product of a gene is localized in mitochondria will support the hypothesis that this protein or gene is involved in energy metabolism. Proteins localized in the cytoskeleton are probably involved in intracellular tra?cking and support. The context of protein functionality is well represented by protein subcellular location. Proteins have various subcellular location patterns [250]. One major category of proteins is synthesized on free ribosomes in the cytoplasm. Soluble proteins
出版日期Book 2005
关键词Alignment; Markov chain; XML; bioinformatics; biology; calculus; classification; clustering; computer; data a
版次1
doihttps://doi.org/10.1007/b138131
isbn_softcover978-1-84996-894-2
isbn_ebook978-1-84628-059-7Series ISSN 1610-3947 Series E-ISSN 2197-8441
issn_series 1610-3947
copyrightSpringer-Verlag London 2005
The information of publication is updating

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https://doi.org/10.1007/978-1-4614-7560-6ies and for accurately estimating the costs of the various query evaluation plans. Our performance studies show that the proposed techniques are very efficient and can provide scientists with interactive secondary structure querying options even on large protein datasets.
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Book 2005ly involved in intracellular tra?cking and support. The context of protein functionality is well represented by protein subcellular location. Proteins have various subcellular location patterns [250]. One major category of proteins is synthesized on free ribosomes in the cytoplasm. Soluble proteins
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AntiClustAl: Multiple Sequence Alignment by Antipole Clusteringces. In particular, a clustering data structure called antipole tree and an approximate linear 1-median computation are used. Our algorithm enjoys a better running time with equivalent alignment quality compared with ClustalW, a widely used tool for multiple sequence alignment. A successful biologic
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Data Mining Methods for a Systematics of Protein Subcellular Locationom the fluorescence microscope images. By selecting the most discriminative features from the entire feature set and recruiting various state-of-the-art classifiers, the system is able to outperform human experts in distinguishing protein patterns. The discriminative features can also be used for ro
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https://doi.org/10.1007/978-3-031-41837-2d on them to make new discoveries on his or her own. The book contains twelve chapters in four parts, namely, overview, sequence and structure alignment, biological data mining, and biological data management. This chapter provides an introduction to the field and describes how the chapters in the book relate to one another.
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