书目名称 | Data Mining in Bioinformatics |
编辑 | Xindong Wu,Lakhmi Jain,Dennis Shasha |
视频video | |
概述 | No known book on this area.First book containing the work of key researchers in biological data mining.Presents new techniques on (a) gene expression data mining, (b) gene mapping for disease detectio |
丛书名称 | Advanced Information and Knowledge Processing |
图书封面 |  |
描述 | 8. 1. 1 Protein Subcellular Location The life sciences have entered the post-genome era where the focus of biologicalresearchhasshiftedfromgenomesequencestoproteinfunctionality. Withwhole-genomedraftsofmouseandhumaninhand,scientistsareputting more and more e?ort into obtaining information about the entire proteome in a given cell type. The properties of a protein include its amino acid sequences, its expression levels under various developmental stages and in di?erenttissues,its3Dstructureandactivesites,itsfunctionalandstructural binding partners, and its subcellular location. Protein subcellular location is important for understanding protein function inside the cell. For example, the observation that the product of a gene is localized in mitochondria will support the hypothesis that this protein or gene is involved in energy metabolism. Proteins localized in the cytoskeleton are probably involved in intracellular tra?cking and support. The context of protein functionality is well represented by protein subcellular location. Proteins have various subcellular location patterns [250]. One major category of proteins is synthesized on free ribosomes in the cytoplasm. Soluble proteins |
出版日期 | Book 2005 |
关键词 | Alignment; Markov chain; XML; bioinformatics; biology; calculus; classification; clustering; computer; data a |
版次 | 1 |
doi | https://doi.org/10.1007/b138131 |
isbn_softcover | 978-1-84996-894-2 |
isbn_ebook | 978-1-84628-059-7Series ISSN 1610-3947 Series E-ISSN 2197-8441 |
issn_series | 1610-3947 |
copyright | Springer-Verlag London 2005 |