| 书目名称 | Damage-Associated Molecular Patternsin Human Diseases | | 副标题 | Volume 2: Danger Sig | | 编辑 | Walter Gottlieb Land | | 视频video | | | 概述 | Describes current knowledge of the role of DAMPs in inducing immune responses.Explores the significance of DAMPs in a wide range of human diseases.Explains how innovative data from immunity and inflam | | 图书封面 |  | | 描述 | .This book is a continuance of the topic: “DAMPs in Human Diseases”, the basics of which were described in a first volume by the same author. This second volume presents our current understanding of the impact of sterile stress/injury-induced innate immune responses on the etiopathogenesis of human diseases by focusing on those diseases that are pathogenetically dominated by DAMPs, i.e., on polytrauma, various solid organ injuries (brain, lung, kidney, liver), atherosclerosis, and cerebro-cardiovascular diseases...Our growing understanding of the pathogenetic function of activating DAMPs and suppressive DAMPs (“SAMPs”) is used as a point of departure to explore how these molecules can be used as biomarkers to extend and improve current diagnostic and prognostic modalities. ..Moreover, this new knowledge about the pathogenetic function of DAMPs and SAMPs is taken as a sound and plausible reason for discussing their implications for present and future treatment of the diseases addressed here. In this context, the focus is on the potential of DAMPs as future therapeutic targets and SAMPs as future therapeutics, applied in strict compliance with safety precautions, as also recommended | | 出版日期 | Book 2020 | | 关键词 | innate immunity; damage-associated molecular patterns; autoimmune diseases; metabolic diseases; traumati | | 版次 | 1 | | doi | https://doi.org/10.1007/978-3-030-53868-2 | | isbn_softcover | 978-3-030-53870-5 | | isbn_ebook | 978-3-030-53868-2 | | copyright | Springer Nature Switzerland AG 2020 |
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发表于 2025-3-21 17:50:10
