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Titlebook: DNA-Protein Interactions; Andrew Travers Book 1993 Andrew Travers 1993 DNA.Promoter.RNA.bacteria.cell.protein.protein complexes.proteins.r

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发表于 2025-3-21 19:57:12 | 显示全部楼层 |阅读模式
书目名称DNA-Protein Interactions
编辑Andrew Travers
视频video
图书封面Titlebook: DNA-Protein Interactions;  Andrew Travers Book 1993 Andrew Travers 1993 DNA.Promoter.RNA.bacteria.cell.protein.protein complexes.proteins.r
描述Our understanding of the mechanisms regulating gene expression, which determine the patterns of growth and development in all living organisms, ultimately involves the elucidation of the detailed and dy­ namic interactions of proteins with nucleic acids -both DNA and RNA. Until recently the commonly presented view of the DNA double helix­ as visualized on the covers of many textbooks and journals - was as a monotonous static straight rod incapable in its own right of directing the processes necessary for the conservation and selective reading of genetic information. This view, although perhaps extreme, was reinforced by the necessary linearity of genetic maps. The reality is that the biological functions of both DNA and RNA are dependent on complex, and sometimes transient, three-dimensional nucleoprotein structures in which genetically distant elements are brought into close spatial proximity. It is in such structures that the enzymatic manipulation of DNA in the essential biological processes as DNA replication, transcription and recombination are effected - the complexes are the mediators of the ‘DNA transactions‘ of Hatch Echols.
出版日期Book 1993
关键词DNA; Promoter; RNA; bacteria; cell; protein; protein complexes; proteins; regulation; transcription
版次1
doihttps://doi.org/10.1007/978-94-011-1480-6
isbn_softcover978-0-412-25990-6
isbn_ebook978-94-011-1480-6
copyrightAndrew Travers 1993
The information of publication is updating

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发表于 2025-3-21 23:33:21 | 显示全部楼层
https://doi.org/10.1007/978-3-319-19551-3r at a local level, affecting perhaps up to a kilobase of DNA, or alternatively more generally affecting the structure and activity of a whole domain comprising many kilobases, or ultimately a whole chromosome.
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The mechanism of RNA chain initiation, process is analogous to other biological processes in which DNA unwinding occurs, such as the initiation of DNA replication and site specific recombination. In these latter processes the unwinding or melting of the duplex is often preceded by the tight wrapping of the DNA on the surface of a large protein complex.
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Chromatin and transcription,r at a local level, affecting perhaps up to a kilobase of DNA, or alternatively more generally affecting the structure and activity of a whole domain comprising many kilobases, or ultimately a whole chromosome.
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