| 书目名称 | DNA Vaccination/Genetic Vaccination |
| 编辑 | Hilary Koprowski (Professor),David B. Weiner (Asso |
| 视频video | |
| 概述 | Enables the reader to understand how to apply important emerging technology to a new generation of vaccines and therapies |
| 丛书名称 | Current Topics in Microbiology and Immunology |
| 图书封面 |  |
| 描述 | Genetic / DNA immunization represents a novel approach to vaccine and immune therapeutic development. The direct injec tion of nucleic acid expression cassettes into a living host results in a limited number of its cells becoming factories for production of the introduced gene products. This host-inappropriate gene expression has important immunological consequences, resulting in the specific immune activation of the host against the gene delivered antigen. The recent demonstration by a number of laboratories that the induced immune responses are functional in experimental models against both specific infectious diseases and cancers is likely to have dramatic consequences for the develop ment of a new generation of experimental vaccines and immune therapies. This technology has the potential to enable the pro duction of vaccines and immune-based therapies that are not only effective immunologically but are accessible to the entire world (rather than just to the most developed nations). Vaccine Development Vaccination against pathogenic microorganisms represents one of the most important advances in the history of medicine. Vaccines, including those against polio, measles, mumps |
| 出版日期 | Book 1998 |
| 关键词 | AIDS; DNA; autoimmune disease; cancer; gene therapy; hepatitis; hepatitis B; immunodeficiency; immunotherapy |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-642-80475-5 |
| isbn_softcover | 978-3-642-80477-9 |
| isbn_ebook | 978-3-642-80475-5Series ISSN 0070-217X Series E-ISSN 2196-9965 |
| issn_series | 0070-217X |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE |
发表于 2025-3-21 18:40:13
