Titlebook: DNA Repair and Human Disease; Adayabalam S. Balajee Book 2006 Springer-Verlag US 2006 DNA.DNA repair.Telomere.Xeroderma pigmentosum.aging.

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Book 2006.DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries. .

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978-1-4899-9899-6Springer-Verlag US 2006

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tational inactivation of a single gene leads to complex phen.DNA Repair and Human Disease highlights the molecular complexities of a few well-known human hereditary disorders that arise due to perturbations in the fidelity of diverse DNA repair machineries. .978-1-4899-9899-6978-0-387-36802-3

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https://doi.org/10.1007/978-3-030-37293-4As highlighted above, the role of oxidative stress in the pathogenesis of AD is a burgeoning field. However, while much is known, much remains unknown as to the impact of therapeutic intervention in patients with disease. Translation of basic scientific findings into efficacious treatment strategies remains to be determined.

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Human Premature Aging Disorders and Dysfunction of DNA Repair,ed by premature onset of age-related phenotypic changes (such as cataract and greying of hair etc) and genome instability. Cells derived from CS patients are defective in DNA repair, and CS patients display severe neurological abnormalities and certain features of premature aging. The accelerated ag