| 书目名称 | DNA Methyltransferases - Role and Function |
| 编辑 | Albert Jeltsch,Renata Z. Jurkowska |
| 视频video | |
| 概述 | Offers comprehensive insights into the newest findings in the field of DNA methylation.Provides in depth knowledge on the structure, enzymatic mechanism as well as the biological roles of DNA methyltr |
| 丛书名称 | Advances in Experimental Medicine and Biology |
| 图书封面 |  |
| 描述 | DNA methyltransferases are important enzymes in a broad range of organisms. Dysfunction of DNA methyltransferases in humans leads to many severe diseases, including cancer. This book focuses on the biochemical properties of these enzymes, describing their structures and mechanisms in bacteria, humans and other species, including plants, and also explains the biological processes of reading of DNA methylation and DNA demethylation. It covers many emerging aspects of the biological roles of DNA methylation functioning as an essential epigenetic mark and describes the role of DNA methylation in diseases. Moreover, the book explains modern technologies, like targeted rewriting of DNA methylation by designed DNA methyltransferases, as well as technological applications of DNA methyltransferases in DNA labelling. Finally, the book summarizes recent methods for the analysis of DNA methylation in human DNA. Overall, this book represents a comprehensive state-of-the-art- work and is a must-havefor advanced researchers in the field of DNA methylation and epigenetics. |
| 出版日期 | Book 20161st edition |
| 关键词 | DNA methylation; Epigenetics; Methyltransferase; Demethylation; DNA labelling; Cancer; Therapeutic targets |
| 版次 | 1 |
| doi | https://doi.org/10.1007/978-3-319-43624-1 |
| isbn_softcover | 978-3-319-82870-1 |
| isbn_ebook | 978-3-319-43624-1Series ISSN 0065-2598 Series E-ISSN 2214-8019 |
| issn_series | 0065-2598 |
| copyright | The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerl |
发表于 2025-3-21 17:31:02
