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派博传思国际中心 »期刊书目

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Titlebook: DNA Methylation: Development, Genetic Disease and Cancer; Walter Doerfler,Petra Böhm Book 2006 The Editor(s) (if applicable) and The Autho

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书目名称DNA Methylation: Development, Genetic Disease and Cancer
编辑Walter Doerfler,Petra Böhm
视频video
概述Includes supplementary material:
丛书名称Current Topics in Microbiology and Immunology
图书封面Titlebook: DNA Methylation: Development, Genetic Disease and Cancer; Walter Doerfler,Petra Böhm Book 2006 The Editor(s) (if applicable) and The Autho
描述.It has become apparent that the genomes of many organisms are characterized by unique patterns of DNA methylation which can differ from genome segment to genome segment and cell type to cell type. These patterns can be instrumental in determining cell type and function. Thus, it is not surprising that studies on the role of DNA methylation now occupy center stage in many fields of biology and medicine such as developmental biology, genetic imprinting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems..
出版日期Book 2006
关键词DNA; biology; cell; development; developmental biology; gene; gene expression; gene therapy; genes; genetics;
版次1
doihttps://doi.org/10.1007/3-540-31181-5
isbn_softcover978-3-642-06830-0
isbn_ebook978-3-540-31181-2Series ISSN 0070-217X Series E-ISSN 2196-9965
issn_series 0070-217X
copyrightThe Editor(s) (if applicable) and The Author(s), under exclusive license to Springer-Verlag GmbH, DE
The information of publication is updating

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Aria, acqua, terra e fuoco - Volume II. Primary epimutations often occur after fertilization and lead to somatic mosaicism. It has been estimated that the rate of primary epimutations is one or two orders of magnitude greater than somatic DNA mutation. Therefore, the contribution of epimutations to human disease is probably underestimated.
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Epimutations in Human Disease,. Primary epimutations often occur after fertilization and lead to somatic mosaicism. It has been estimated that the rate of primary epimutations is one or two orders of magnitude greater than somatic DNA mutation. Therefore, the contribution of epimutations to human disease is probably underestimated.
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Genome-wide Analysis of DNA Methylation Changes in Human Malignancies,et in clinical studies, it is of utmost importance to define potential target sequences that could be used as diagnostic or prognostic markers. We conclude the review by outlining possible scenarios that may explain tumor type-specific DNA methylation patterns described by assays evaluating genome-wide levels of DNA methylation.
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Book 2006nting, genetic disease, tumor biology, gene therapy, cloning of organisms and others. Once again, basic research in molecular biology has provided the essential foundation for investigations of biomedical problems..
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