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Titlebook: DNA Fingerprinting: State of the Science; S. D. J. Pena,R. Chakraborty,Alec J. Jeffreys Book 1993 Springer Basel AG 1993 databases.evoluti

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,Work in Progress — die neuen Projekte, high degree of consanguinity: (i) deficiency of observed heterozygotes at the autosomal loci and (ii) almost all men carry the same Y chromosomal allele. Nevertheless in the Yanomami village two thirds of the described autosomal microsatellite alleles were identified. Several paternities were clarified.
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Variation of minisatellites in chemically induced mutagenesis and in gene amplificationll lines carrying amplification of the CAD gene. The DNA fingerprint analysis showed a variation in minisatellite regions in 3 lines while no variation was observed in independent colonies from the CHO parental cell line. The results suggest that these sequences may be hot spots for recombination during gene amplification.
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The forensic significance of various reference population databases for estimating the rarity of var92), for deriving statistical estimates of DNA profile frequencies. Comparisons across major population groups provide reasonable, reliable, and meaningful estimates of DNA profile frequencies without forensically significant consequences.
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Book 1993mu1tilocus probes capable of simultaneously revealing hypervari­ ability at many loci in the human genome and called the procedure DNA fingerprinting. It was a royal birth in the best British tradition. In a few months the emerging technique had permitted the denouement of hith­ erto insoluble immig
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