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Titlebook: DNA Conformation and Transcription; Takashi Ohyama Book 2005 Springer-Verlag US 2005 Chromosom.DNA.Promoter.RNA.Termination.gene expressio

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书目名称DNA Conformation and Transcription
编辑Takashi Ohyama
视频video
概述Focuses on functional aspects of DNA structures (conformations), rather than structure and conformation themselves.Description of human triplet-repeat diseases and mechanisms of mammalian sex determin
丛书名称Molecular Biology Intelligence Unit
图书封面Titlebook: DNA Conformation and Transcription;  Takashi Ohyama Book 2005 Springer-Verlag US 2005 Chromosom.DNA.Promoter.RNA.Termination.gene expressio
描述.Despite remarkable progress in genome science, we are still far from a clear understanding of how genomic DNA is packaged without entanglement into a nucleus, how genes are wrapped up in chromatin, how chromatin structure is faithfully inherited from mother to daughter cells, and how the differential expression of genes is enabled in a given cell type. Exploring and answering these questions constitutes one of the next frontiers in the 21st century...We are just beginning to appreciate how Multifarious DNA structures provide additional structural and functional dimensions to chromatin organization and gene expression. DNA Conformation and Transcription is the first book that compiles the fruits of the studies that have been performed to date to solve the riddle ‘written’ in DNA conformation ("conformation code"). This book provides a comprehensive overview of the field by covering history of the field, up-to-date topics, clarifications of present day research, and future perspective of what is still to be discovered. Thus, it serves as an invaluable source of information on the "conformation code". .
出版日期Book 2005
关键词Chromosom; DNA; Promoter; RNA; Termination; gene expression; genes; molecular mechanisms; proteins; regulatio
版次1
doihttps://doi.org/10.1007/0-387-29148-2
isbn_softcover978-1-4899-9507-0
isbn_ebook978-0-387-29148-2Series ISSN 1431-0414
issn_series 1431-0414
copyrightSpringer-Verlag US 2005
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Static Arbitrage: Forwards and Futurespercoiling of the template DNA. Furthermore, packaging of genomic DNA into chromatin in eukaryotes raises another type of relation. DNA supercoiling can affect transcription through modulation of the chromatin structure.
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https://doi.org/10.1007/978-3-662-57475-1ns, particularly bending, of the double helix. The A-tract curvature, which modulates these processes, has thus been a subject of long-standing interest. Here we describe the ongoing evolution of models developed to account for the sequence-dependent bending and curvature of DNA, namely the AA-wedge
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